IGLL1 Produkte
(Immunoglobulin lambda-Like Polypeptide 1 (IGLL1))
Kategorien
The preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. This gene encodes one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. This gene does not undergo rearrangement. Mutations in this gene can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Ausgewählte IGLL1 Kategorien
IGLL1 Antikörper
High quality antibodies with extensive validation data.
IGLL1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene IGLL1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IP
Validierungen
- (4)
Kat. Nr.
ABIN516975
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, ICC
Validierungen
- (4)
Kat. Nr.
ABIN2118554
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB
Validierungen
- (2)
Kat. Nr.
ABIN516973
Menge
50 μg
Datenblatt
Datenblatt
Empfohlene IGLL1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1307605
Menge
25 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN2129922
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7415680
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren IGLL1 Produkten
: "VpreB1/VpreB2/lambda 5 triple-deficient mice show impaired B cell development but functional allelic exclusion of the IgH locus." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 168, Issue 12, pp. 6286-93, (2002) (PubMed).: "The identification of a nonclassical cadherin expressed during B cell development and its interaction with surrogate light chain." in: The Journal of biological chemistry, Vol. 275, Issue 40, pp. 31134-44, (2000) (PubMed).
: "Review article: role of the surrogate light chain and the pre-B-cell receptor in mouse B-cell development." in: Immunology, Vol. 101, Issue 4, pp. 435-41, (2000) (PubMed).
: "Repertoire selection by pre-B-cell receptors and B-cell receptors, and genetic control of B-cell development from immature to mature B cells." in: Immunological reviews, Vol. 175, pp. 33-46, (2000) (PubMed).
: "Antigen receptor engagement turns off the V(D)J recombination machinery in human tonsil B cells." in: The Journal of experimental medicine, Vol. 188, Issue 4, pp. 765-72, (1998) (PubMed).
: "IL-2 receptor alpha chain (CD25, TAC) expression defines a crucial stage in pre-B cell development." in: International immunology, Vol. 6, Issue 8, pp. 1257-64, (1995) (PubMed).
: "Precursor B cells of mouse bone marrow express two different complexes with the surrogate light chain on the surface." in: European journal of immunology, Vol. 25, Issue 2, pp. 446-50, (1995) (PubMed).
: "The expression of Vpre-B/lambda 5 surrogate light chain in early bone marrow precursor B cells of normal and B cell-deficient mutant mice." in: Cell, Vol. 77, Issue 1, pp. 133-43, (1994) (PubMed).
: "A complex of glycoproteins is associated with VpreB/lambda 5 surrogate light chain on the surface of mu heavy chain-negative early precursor B cell lines." in: The Journal of experimental medicine, Vol. 178, Issue 2, pp. 469-78, (1993) (PubMed).
Synonyme und alternative Namen zu IGLL1
immunoglobulin lambda like polypeptide 1 (IGLL1), immunoglobulin lambda-like polypeptide 1 (IGLL1), immunoglobulin lambda-like polypeptide 1 (Igll1), 14.1, AGM2, BB139905, CD179b, Igl-5, IGL1, IGL5, IGLJ14.1, IGLL, Igll, IGLL1, Igll1, IGLV, IGO, IGVPB, Lambda5, MGC151892, VPREB2Bezeichner auf Proteinebene für IGLL1
- CD179 antigen-like family member B
- CD179b antigen
- Pre-B lymphocyte-specific protein-2
- ig lambda-5
- immunoglobulin omega polypeptide chain
- immunoglobulin-related 14.1 protein
- immunoglobulin-related protein 14.1
- lambda5
- Ig lambda chain V-1 region
- Ig light chain variable region
- immunoglobulin lambda-like polypeptide 1
- Lambda5
- Immunoglobulin lambda-like polypeptide 1-like
- immunoglobulin lambda chain 5
- lambda 5
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