IL-10RA Produkte
(Interleukin 10 Receptor, alpha (IL10RA))
Kategorien
The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. [provided by RefSeq, Jan 2009].
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Ausgewählte IL-10RA Kategorien
IL-10RA Antikörper
High quality antibodies with extensive validation data.
IL-10RA ELISA Kits
Reliable ELISA kits for a wide range of species.
IL-10RA Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene IL-10RA Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, ICC
Validierungen
- (8)
Kat. Nr.
ABIN7433870
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IF
Validierungen
- (7)
Kat. Nr.
ABIN3022615
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
IHC, IF
Validierungen
- (4)
Kat. Nr.
ABIN7259833
Menge
200 μL
Datenblatt
Datenblatt
Empfohlene IL-10RA ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6956986
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6956987
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6956988
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene IL-10RA Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (5)
Kat. Nr.
ABIN7274906
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Cynomolgus
Source
HEK-293 Cells
Validierungen
- (4)
Kat. Nr.
ABIN7274878
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
Kat. Nr.
ABIN6253272
Menge
50 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren IL-10RA Produkten
: "Functional analysis of bovine interleukin-10 receptor alpha in response to Mycobacterium avium subsp. paratuberculosis lysate using CRISPR/Cas9." in: BMC genetics, Vol. 21, Issue 1, pp. 121, (2020) (PubMed).: "MYD88 L265P mutation promoted malignant B cell resistance against T cell-mediated cytotoxicity via upregulating the IL-10/STAT3 cascade." in: International immunopharmacology, Vol. 64, pp. 394-400, (2019) (PubMed).
: "Enhanced gut barrier integrity sensitizes colon cancer to immune therapy." in: Oncoimmunology, Vol. 7, Issue 11, pp. e1498438, (2018) (PubMed).
: "Synthetic Lethal Screen Demonstrates That a JAK2 Inhibitor Suppresses a BCL6-dependent IL10RA/JAK2/STAT3 Pathway in High Grade B-cell Lymphoma." in: The Journal of biological chemistry, Vol. 291, Issue 32, pp. 16686-98, (2016) (PubMed).
: "cmvIL-10 stimulates the invasive potential of MDA-MB-231 breast cancer cells." in: PLoS ONE, Vol. 9, Issue 2, pp. e88708, (2014) (PubMed).
: "Regulation of interleukin-10 receptor ubiquitination and stability by beta-TrCP-containing ubiquitin E3 ligase." in: PLoS ONE, Vol. 6, Issue 11, pp. e27464, (2011) (PubMed).
: "Role for IL-10 in suppression mediated by peptide-induced regulatory T cells in vivo." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 170, Issue 3, pp. 1240-8, (2003) (PubMed).
: "Regulatory activity of autocrine IL-10 on dendritic cell functions." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 166, Issue 7, pp. 4312-8, (2001) (PubMed).
: "Cutting edge: interactions through the IL-10 receptor regulate autoimmune diabetes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 167, Issue 11, pp. 6087-91, (2001) (PubMed).
: "IL-10 inhibits macrophage activation and proliferation by distinct signaling mechanisms: evidence for Stat3-dependent and -independent pathways." in: The EMBO journal, Vol. 17, Issue 4, pp. 1006-18, (1998) (PubMed).
Synonyme und alternative Namen zu IL-10RA
interleukin 10 receptor subunit alpha (IL10RA), interleukin 10 receptor, alpha (Il10ra), interleukin 10 receptor subunit alpha (Il10ra), AW553859, CD210, CD210a, CDw210, CDW210A, CDw210a, HIL-10R, IL-10R1, IL10R, Il10r, IL10R1, IL10RA, mIL-10RBezeichner auf Proteinebene für IL-10RA
- interleukin 10 receptor 1
- interleukin-10 receptor subunit alpha
- interleukin 10 receptor, alpha
- interleukin-10 receptor subunit alpha-like
- IL-10 receptor subunit alpha
- IL-10R subunit 1
- IL-10R subunit alpha
- IL-10RA
- interleukin-10 receptor alpha chain
- interleukin-10 receptor subunit 1
- IL-10R1
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