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IL-10RA Produkte

(Interleukin 10 Receptor, alpha (IL10RA))

Kategorien

The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. [provided by RefSeq, Jan 2009].

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Ausgewählte IL-10RA Kategorien

IL-10RA Antikörper

High quality antibodies with extensive validation data.

IL-10RA ELISA Kits

Reliable ELISA kits for a wide range of species.

IL-10RA Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene IL-10RA Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, IP, ICC
Validierungen
  • (8)
Kat. Nr. ABIN7433870
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IF
Validierungen
  • (7)
Kat. Nr. ABIN3022615
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation IHC, IF
Validierungen
  • (4)
Kat. Nr. ABIN7259833
Menge 200 μL
Datenblatt Datenblatt

Empfohlene IL-10RA ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6956986
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6956987
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6956988
Menge 96 tests
Datenblatt Datenblatt

Empfohlene IL-10RA Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (5)
Kat. Nr. ABIN7274906
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Cynomolgus
Source HEK-293 Cells
Validierungen
  • (4)
Kat. Nr. ABIN7274878
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
Kat. Nr. ABIN6253272
Menge 50 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren IL-10RA Produkten

Mallikarjunappa, Shandilya, Sharma, Lamers, Bissonnette, Karrow, Meade: "Functional analysis of bovine interleukin-10 receptor alpha in response to Mycobacterium avium subsp. paratuberculosis lysate using CRISPR/Cas9." in: BMC genetics, Vol. 21, Issue 1, pp. 121, (2020) (PubMed).

Qiu, Gong, Xu, Cheng, Gao, Chen, Hu, Yang: "MYD88 L265P mutation promoted malignant B cell resistance against T cell-mediated cytotoxicity via upregulating the IL-10/STAT3 cascade." in: International immunopharmacology, Vol. 64, pp. 394-400, (2019) (PubMed).

Bhutiani, Li, Anderson, Gallagher, De Jesus, Singh, Jala, Fraig, Gu, Egilmez: "Enhanced gut barrier integrity sensitizes colon cancer to immune therapy." in: Oncoimmunology, Vol. 7, Issue 11, pp. e1498438, (2018) (PubMed).

Beck, Zobel, Barber, Evans, Lezina, Allchin, Blades, Elliott, Lord, Ashworth, Porter, Wagner: "Synthetic Lethal Screen Demonstrates That a JAK2 Inhibitor Suppresses a BCL6-dependent IL10RA/JAK2/STAT3 Pathway in High Grade B-cell Lymphoma." in: The Journal of biological chemistry, Vol. 291, Issue 32, pp. 16686-98, (2016) (PubMed).

Valle Oseguera, Spencer: "cmvIL-10 stimulates the invasive potential of MDA-MB-231 breast cancer cells." in: PLoS ONE, Vol. 9, Issue 2, pp. e88708, (2014) (PubMed).

Jiang, Lu, Yuan, Liu: "Regulation of interleukin-10 receptor ubiquitination and stability by beta-TrCP-containing ubiquitin E3 ligase." in: PLoS ONE, Vol. 6, Issue 11, pp. e27464, (2011) (PubMed).

Sundstedt, ONeill, Nicolson, Wraith: "Role for IL-10 in suppression mediated by peptide-induced regulatory T cells in vivo." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 170, Issue 3, pp. 1240-8, (2003) (PubMed).

Corinti, Albanesi, la Sala, Pastore, Girolomoni: "Regulatory activity of autocrine IL-10 on dendritic cell functions." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 166, Issue 7, pp. 4312-8, (2001) (PubMed).

Phillips, Parish, Drage, Cooke: "Cutting edge: interactions through the IL-10 receptor regulate autoimmune diabetes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 167, Issue 11, pp. 6087-91, (2001) (PubMed).

OFarrell, Liu, Moore, Mui: "IL-10 inhibits macrophage activation and proliferation by distinct signaling mechanisms: evidence for Stat3-dependent and -independent pathways." in: The EMBO journal, Vol. 17, Issue 4, pp. 1006-18, (1998) (PubMed).

Synonyme und alternative Namen zu IL-10RA

interleukin 10 receptor subunit alpha (IL10RA), interleukin 10 receptor, alpha (Il10ra), interleukin 10 receptor subunit alpha (Il10ra), AW553859, CD210, CD210a, CDw210, CDW210A, CDw210a, HIL-10R, IL-10R1, IL10R, Il10r, IL10R1, IL10RA, mIL-10R

Bezeichner auf Proteinebene für IL-10RA

  • interleukin 10 receptor 1
  • interleukin-10 receptor subunit alpha
  • interleukin 10 receptor, alpha
  • interleukin-10 receptor subunit alpha-like
  • IL-10 receptor subunit alpha
  • IL-10R subunit 1
  • IL-10R subunit alpha
  • IL-10RA
  • interleukin-10 receptor alpha chain
  • interleukin-10 receptor subunit 1
  • IL-10R1
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