IL12RB1 Produkte
(Interleukin 12 Receptor beta 1 (IL12RB1))
Kategorien
The protein encoded by this gene is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex. This protein forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The lack of expression of this gene was found to result in the immunodeficiency of patients with severe mycobacterial and Salmonella infections. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].
antibodies-online.com steht für hochwertige Forschungsprodukte. Suchen, finden und bestellen Sie Tools mit umfangreichen Validierungsdaten, Bildern, Referenzen. Unser wissenschaftlicher Kundenservice steht Ihnen jederzeit zur Verfügung, wenn Sie Fragen zur Auswahl oder Anwendung unserer Produkte haben.
Ausgewählte IL12RB1 Kategorien
IL12RB1 Antikörper
High quality antibodies with extensive validation data.
IL12RB1 ELISA Kits
Reliable ELISA kits for a wide range of species.
IL12RB1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene IL12RB1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse, Rat
Applikation
WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p)
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN747863
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Rat
Applikation
IHC, IF
Validierungen
- (2)
Kat. Nr.
ABIN7256826
Menge
200 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IP
Validierungen
- (2)
Kat. Nr.
ABIN517100
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene IL12RB1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6957018
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6730742
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6730741
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene IL12RB1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN7275013
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN6731329
Menge
200 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1307680
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren IL12RB1 Produkten
: "Contribution of IL-12/IL-35 common subunit p35 to maintaining the testicular immune privilege." in: PLoS ONE, Vol. 9, Issue 4, pp. e96120, (2014) (PubMed).: "Blood CD4+CD45RO+CXCR5+ T cells are decreased but partially functional in signal transducer and activator of transcription 3 deficiency." in: The Journal of allergy and clinical immunology, Vol. 131, Issue 4, pp. 1146-56, 1156.e1-5, (2013) (PubMed).
: "IL-21 in the bone marrow microenvironment contributes to IgM secretion and proliferation of malignant cells in Waldenstrom macroglobulinemia." in: Blood, Vol. 120, Issue 18, pp. 3774-82, (2012) (PubMed).
: "Complementary IL-23 and IL-27 anti-tumor activities cause strong inhibition of human follicular and diffuse large B-cell lymphoma growth in vivo." in: Leukemia, Vol. 26, Issue 6, pp. 1365-74, (2012) (PubMed).
: "Association of single nucleotide polymorphisms in the IL-12 (IL-12A and B) and IL-12 receptor (IL-12Rbeta1 and beta2) genes and gene-gene interactions with atopic dermatitis in Koreans." in: Journal of dermatological science, Vol. 57, Issue 3, pp. 199-206, (2010) (PubMed).
: "Human intestinal intraepithelial lymphocytes keep TNF alpha levels low by cell uptake and feedback inhibition of transcription." in: Cellular immunology, Vol. 241, Issue 1, pp. 7-13, (2006) (PubMed).
: "A novel form of complete IL-12/IL-23 receptor beta1 deficiency with cell surface-expressed nonfunctional receptors." in: Blood, Vol. 104, Issue 7, pp. 2095-101, (2004) (PubMed).
: "IL-12 receptor beta 2 (IL-12R beta 2)-deficient mice are defective in IL-12-mediated signaling despite the presence of high affinity IL-12 binding sites." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 165, Issue 11, pp. 6221-8, (2000) (PubMed).
: "Characterization of mouse interleukin-12 p40 homodimer binding to the interleukin-12 receptor subunits." in: European journal of immunology, Vol. 29, Issue 6, pp. 2007-13, (1999) (PubMed).
: "Analysis of the multiple interactions between IL-12 and the high affinity IL-12 receptor complex." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 160, Issue 5, pp. 2174-9, (1998) (PubMed).
Synonyme und alternative Namen zu IL12RB1
interleukin 12 receptor subunit beta 1 (Il12rb1), interleukin 12 receptor subunit beta 1 (IL12RB1), interleukin 12 receptor, beta 1 (Il12rb1), CD212, IL-12R, IL-12R-BETA1, IL-12R[b], Il12rb, IL12RB, IL12RB1Bezeichner auf Proteinebene für IL12RB1
- interleukin-12 receptor subunit beta-1
- interleukin 12 receptor, beta 1
- IL12 receptor beta 1 subunit
- interleukin-12 receptor subunit beta-1-like
- IL-12 receptor beta component
- IL-12 receptor subunit beta-1
- IL-12R subunit beta-1
- interleukin-12 receptor beta-1 chain
- IL-12R-beta-1
- Interleukin-12 receptor beta-1 chain precursor (IL-12R-beta1) (Interleukin-12 receptor beta) (IL-12 receptor beta component)
Haben Sie etwas anderes gesucht?
Sie sind hier:
