IL7R Produkte
(Interleukin 7 Receptor (IL7R))
Kategorien
The protein encoded by this gene is a receptor for interleukine 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukine 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in the V(D)J recombination during lymphocyte development. This protein is also found to control the accessibility of the TCR gamma locus by STAT5 and histone acetylation. Knockout studies in mice suggested that blocking apoptosis is an essential function of this protein during differentiation and activation of T lymphocytes. The functional defects in this protein may be associated with the pathogenesis of the severe combined immunodeficiency (SCID). [provided by RefSeq, Jul 2008].
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Ausgewählte IL7R Kategorien
IL7R Antikörper
High quality antibodies with extensive validation data.
IL7R ELISA Kits
Reliable ELISA kits for a wide range of species.
IL7R Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene IL7R Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC (p), ICC, IHC (fro)
Validierungen
- (7)
Kat. Nr.
ABIN7434320
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
FACS, WB, ELISA
Validierungen
- (5)
Kat. Nr.
ABIN7193312
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
FACS, IP, Neut
Validierungen
- (39)
- (3)
Kat. Nr.
ABIN6923149
Menge
0.1 mg
Datenblatt
Datenblatt
Empfohlene IL7R ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6968025
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6957181
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6957182
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene IL7R Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (4)
Kat. Nr.
ABIN7274965
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN7274967
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN7274964
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren IL7R Produkten
: "Influence of glucose and insulin in human adipogenic differentiation models with adipose-derived stem cells." in: Adipocyte, Vol. 8, Issue 1, pp. 254-264, (2019) (PubMed).: "Increased soluble IL-7 receptor concentrations associate with improved IL-7 therapy outcomes in SIV-infected ART-treated Rhesus macaques." in: PLoS ONE, Vol. 12, Issue 12, pp. e0188427, (2018) (PubMed).
: "Aberrant plasma IL-7 and soluble IL-7 receptor levels indicate impaired T-cell response to IL-7 in human tuberculosis." in: PLoS pathogens, Vol. 13, Issue 6, pp. e1006425, (2017) (PubMed).
: "Frontline Science: A hyporesponsive subset of rat NK cells negative for Ly49s3 and NKR-P1B are precursors to the functionally mature NKR-P1B+subset." in: Journal of leukocyte biology, Vol. 102, Issue 6, pp. 1289-1298, (2017) (PubMed).
: "DNA Methylation Regulates the Differential Expression of CX3CR1 on Human IL-7Rαlow and IL-7Rαhigh Effector Memory CD8+ T Cells with Distinct Migratory Capacities to the Fractalkine." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 6, pp. 2861-9, (2015) (PubMed).
: "Tubulation of endosomal structures in human dendritic cells by Toll-like receptor ligation and lymphocyte contact accompanies antigen cross-presentation." in: The Journal of biological chemistry, Vol. 289, Issue 1, pp. 520-8, (2014) (PubMed).
: "IL-7 receptor recovery on CD8 T-cells isolated from HIV+ patients is inhibited by the HIV Tat protein." in: PLoS ONE, Vol. 9, Issue 7, pp. e102677, (2014) (PubMed).
: "Activated innate lymphoid cells are associated with a reduced susceptibility to graft-versus-host disease." in: Blood, Vol. 124, Issue 5, pp. 812-21, (2014) (PubMed).
: "High numbers of differentiated effector CD4 T cells are found in patients with cancer and correlate with clinical response after neoadjuvant therapy of breast cancer." in: Cancer research, Vol. 74, Issue 8, pp. 2204-16, (2014) (PubMed).
: "An immunological biomarker to predict MTX response in early RA." in: Annals of the rheumatic diseases, Vol. 73, Issue 11, pp. 2047-53, (2014) (PubMed).
Synonyme und alternative Namen zu IL7R
interleukin 7 receptor (IL7R), interleukin 7 receptor (Il7r), CD127, CDW127, IL-7R-alpha, IL-7RA, IL-7Ralpha, IL7R, IL7RA, ILRABezeichner auf Proteinebene für IL7R
- interleukin 7 receptor
- interleukin-7 receptor subunit alpha-like
- IL-7 receptor alpha chain
- IL-7 receptor subunit alpha
- IL-7R subunit alpha
- IL-7R-alpha
- IL-7RA
- interleukin 7 receptor alpha chain
- interleukin-7 receptor subunit alpha
- CD127 antigen
- interleukin 7 receptor isoform H5-6
- Interleukin-7 receptor subunit alpha-like protein
- Interleukin-7 receptor subunit alpha
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