IMPDH2 Produkte
(IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2))
Kategorien
This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation. [provided by RefSeq, Jul 2008].
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Ausgewählte IMPDH2 Kategorien
IMPDH2 Antikörper
High quality antibodies with extensive validation data.
IMPDH2 ELISA Kits
Reliable ELISA kits for a wide range of species.
IMPDH2 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene IMPDH2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IP, RNAi
Validierungen
- (1)
- (4)
Kat. Nr.
ABIN561488
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC, IF
Validierungen
- (4)
Kat. Nr.
ABIN7156292
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IF, IHC (p), ICC
Validierungen
- (4)
Kat. Nr.
ABIN2855167
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene IMPDH2 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6967575
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6967574
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6956714
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene IMPDH2 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1307895
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7123412
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7408207
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren IMPDH2 Produkten
: "Myc-dependent purine biosynthesis affects nucleolar stress and therapy response in prostate cancer." in: Oncotarget, Vol. 6, Issue 14, pp. 12587-602, (2015) (PubMed).: "IMPDH2 mediate radioresistance and chemoresistance in osteosarcoma cells." in: European review for medical and pharmacological sciences, Vol. 18, Issue 20, pp. 3038-44, (2014) (PubMed).
: "A purine nucleotide biosynthesis enzyme guanosine monophosphate reductase is a suppressor of melanoma invasion." in: Cell reports, Vol. 5, Issue 2, pp. 493-507, (2013) (PubMed).
: "Proteomic analysis of the effects of the immunomodulatory mycotoxin deoxynivalenol." in: Proteomics, Vol. 11, Issue 10, pp. 1903-14, (2011) (PubMed).
: "Antiproliferative effects of AVN944, a novel inosine 5-monophosphate dehydrogenase inhibitor, in prostate cancer cells." in: International journal of cancer, Vol. 123, Issue 10, pp. 2294-302, (2008) (PubMed).
: "Direct role of nucleotide metabolism in C-MYC-dependent proliferation of melanoma cells." in: Cell cycle (Georgetown, Tex.), Vol. 7, Issue 15, pp. 2392-400, (2008) (PubMed).
: "Prognostic significance of drug-regulated genes in high-grade osteosarcoma." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 20, Issue 10, pp. 1085-94, (2007) (PubMed).
Synonyme und alternative Namen zu IMPDH2
inosine monophosphate dehydrogenase 2 (IMPDH2), IMP (inosine 5'-monophosphate) dehydrogenase 2 (impdh2.S), IMP (inosine 5'-monophosphate) dehydrogenase 2 (impdh2), inosine monophosphate dehydrogenase 2 (impdh2), inosine monophosphate dehydrogenase 2 (Impdh2), inosine 5'-phosphate dehydrogenase 2 (impdh2), cb635, imp2, IMPD, impd2, IMPD2, IMPD 2, impdh-ii, IMPDH-II, impdh2, IMPDH 2, wu:fb64g02, wu:fc43f09Bezeichner auf Proteinebene für IMPDH2
- IMP (inosine monophosphate) dehydrogenase 2
- inosine monophosphate dehydrogenase 2
- IMP (inosine 5'-monophosphate) dehydrogenase 2
- hCG2002013-like
- inosine-5'-monophosphate dehydrogenase 2-like
- IMP oxireductase 2
- IMPD 2
- IMPDH 2
- inosine 5' phosphate dehydrogenase 2
- inosine monophosphate dehydrogenase type II
- inosine-5'-monophosphate dehydrogenase 2
- IMP dehydrogenase 2
- IMPDH-II
- inosine 5'-phosphate dehydrogenase 2
- inosine 5-monophosphate dehydrogenase 2
- IMP dehydrogenase type II
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