Integrin AlphaV, Integrin Beta3 Produkte
(Integrin AlphaV, Integrin Beta3 (ITGAV/ITGB3))
Kategorien
ITAGV encodes integrin alpha chain V. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The I-domain containing integrin alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, that combine with multiple integrin beta chains to form different integrins. Among the known associating beta chains (beta chains 1,3,5,6, and 8\; 'ITGB1', 'ITGB3', 'ITGB5', 'ITGB6', and 'ITGB8'), each can interact with extracellular matrix ligands\; the alpha V beta 3 integrin, perhaps the most studied of these, is referred to as the Vitronectin receptor (VNR). In addition to adhesion, many integrins are known to facilitate signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2009].
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Ausgewählte Integrin AlphaV, Integrin Beta3 Kategorien
Integrin AlphaV, Integrin Beta3 Antikörper
High quality antibodies with extensive validation data.
Integrin AlphaV, Integrin Beta3 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene Integrin AlphaV, Integrin Beta3 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
FACS, WB, IF (cc), IF (p), IHC (fro), ELISA, IHC (p)
Validierungen
- (10)
- (2)
Kat. Nr.
ABIN674784
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
FACS, IHC
Validierungen
- (3)
- (1)
Kat. Nr.
ABIN2191903
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Chicken, Human
Applikation
FACS, IP, IHC (fro)
Validierungen
- (1)
Kat. Nr.
ABIN7013947
Menge
0.1 mg
Datenblatt
Datenblatt
Empfohlene Integrin AlphaV, Integrin Beta3 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6968072
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene Integrin AlphaV, Integrin Beta3 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (4)
Kat. Nr.
ABIN7275059
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN7275055
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN7275060
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren Integrin AlphaV, Integrin Beta3 Produkten
: "Radioiodinated bicyclic RGD peptide for imaging integrin αvβ3 in cancers." in: Biochemical and biophysical research communications, Vol. 528, Issue 1, pp. 168-173, (2021) (PubMed).: "GSH-sensitive Pt(IV) prodrug-loaded phase-transitional nanoparticles with a hybrid lipid-polymer shell for precise theranostics against ovarian cancer." in: Theranostics, Vol. 9, Issue 4, pp. 1047-1065, (2019) (PubMed).
: "The urokinase-type plasminogen activator system as drug target in retinitis pigmentosa: New pre-clinical evidence in the rd10 mouse model." in: Journal of cellular and molecular medicine, Vol. 23, Issue 8, pp. 5176-5192, (2019) (PubMed).
: "The post-abscission midbody is an intracellular signaling organelle that regulates cell proliferation." in: Nature communications, Vol. 10, Issue 1, pp. 3181, (2019) (PubMed).
: "cRGD peptide installation on cisplatin-loaded nanomedicines enhances efficacy against locally advanced head and neck squamous cell carcinoma bearing cancer stem-like cells." in: Journal of controlled release : official journal of the Controlled Release Society, Vol. 261, pp. 275-286, (2018) (PubMed).
: "Osteopontin-integrin engagement induces HIF-1α-TCF12-mediated endothelial-mesenchymal transition to exacerbate colorectal cancer." in: Oncotarget, Vol. 9, Issue 4, pp. 4998-5015, (2018) (PubMed).
: "HLA Class II-Triggered Signaling Cascades Cause Endothelial Cell Proliferation and Migration: Relevance to Antibody-Mediated Transplant Rejection." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 200, Issue 7, pp. 2372-2390, (2018) (PubMed).
: "Evaluation of a dimeric-cRGD peptide for targeted PET-CT imaging of peripheral angiogenesis in diabetic mice." in: Scientific reports, Vol. 8, Issue 1, pp. 5401, (2018) (PubMed).
: "Acidic preconditioning of endothelial colony-forming cells (ECFC) promote vasculogenesis under proinflammatory and high glucose conditions in vitro and in vivo." in: Stem cell research & therapy, Vol. 9, Issue 1, pp. 120, (2018) (PubMed).
: "Mechanosignaling activation of TGFβ maintains intervertebral disc homeostasis." in: Bone research, Vol. 5, pp. 17008, (2017) (PubMed).
Synonyme und alternative Namen zu Integrin AlphaV, Integrin Beta3
integrin subunit alpha V (ITGAV), CD51, MSK8, VNRA, VTNRBezeichner auf Proteinebene für Integrin AlphaV, Integrin Beta3
- antigen identified by monoclonal antibody L230
- integrin alpha-V
- integrin alphaVbeta3
- integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
- vitronectin receptor subunit alpha
- vitronectin receptor alpha subunit
- integrin alpha V subunit
- alphaV integrin
- integrin alpha v
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