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Integrin beta 4 Produkte

(Integrin beta 4 (ITGB4))
Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Ausgewählte Integrin beta 4 Kategorien

Integrin beta 4 Antikörper

High quality antibodies with extensive validation data.

Integrin beta 4 ELISA Kits

Reliable ELISA kits for a wide range of species.

Integrin beta 4 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene Integrin beta 4 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, FACS, ELISA
Validierungen
  • (1)
  • (6)
Kat. Nr. ABIN1724805
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, FACS, ELISA
Validierungen
  • (6)
Kat. Nr. ABIN5611133
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, ELISA, IF
Validierungen
  • (4)
Kat. Nr. ABIN7156486
Menge 100 μg
Datenblatt Datenblatt

Empfohlene Integrin beta 4 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6956849
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validierungen
Kat. Nr. ABIN1380463
Menge 2 x 96 tests
Datenblatt Datenblatt
Reaktivität Cow
Analytical Method Quantitative
Validierungen
Kat. Nr. ABIN1055086
Menge 96 tests
Datenblatt Datenblatt

Empfohlene Integrin beta 4 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7123472
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1308213
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Baculovirus infected Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN6388181
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren Integrin beta 4 Produkten

Giampieri, Piva, Occhipinti, Bittoni, Righetti, Pagliaretta, Murrone, Bianchi, Amantini, Giulietti, Ricci, Principato, Santoni, Berardi, Cascinu: "Clinical impact of different exosomes' protein expression in pancreatic ductal carcinoma patients treated with standard first line palliative chemotherapy." in: PLoS ONE, Vol. 14, Issue 5, pp. e0215990, (2019) (PubMed).

Russo, Klein, Lim, Solis, Machado, Hiroyasu, Nabai, Shen, Zeglinski, Zhao, Oram, Lennox, Van Laeken, Carr, Crawford, Franzke, Overall, Granville: "Granzyme B is elevated in autoimmune blistering diseases and cleaves key anchoring proteins of the dermal-epidermal junction." in: Scientific reports, Vol. 8, Issue 1, pp. 9690, (2018) (PubMed).

Rajan, Persson, Frängsmyr, Olofsson, Sandblad, Heino, Takada, Mould, Schnapp, Gall, Arnberg: "Enteric Species F Human Adenoviruses use Laminin-Binding Integrins as Co-Receptors for Infection of Ht-29 Cells." in: Scientific reports, Vol. 8, Issue 1, pp. 10019, (2018) (PubMed).

Storm, Persson, Skalman, Frängsmyr, Lindström, Rankin, Lundmark, Domellöf, Arnberg: "Human Adenovirus Type 37 Uses αVβ1 and α3β1 Integrins for Infection of Human Corneal Cells." in: Journal of virology, Vol. 91, Issue 5, (2017) (PubMed).

Feng, Chen, Ding, Fu, Yang, Deng, Zeng: "P2X7R blockade prevents NLRP3 inflammasome activation and brain injury in a rat model of intracerebral hemorrhage: involvement of peroxynitrite." in: Journal of neuroinflammation, Vol. 12, pp. 190, (2016) (PubMed).

Hoshino, Costa-Silva, Shen, Rodrigues, Hashimoto, Tesic Mark, Molina, Kohsaka, Di Giannatale, Ceder, Singh, Williams, Soplop, Uryu, Pharmer, King, Bojmar, Davies, Ararso, Zhang, Zhang, Hernandez et al.: "Tumour exosome integrins determine organotropic metastasis. ..." in: Nature, Vol. 527, Issue 7578, pp. 329-35, (2015) (PubMed).

Wu, Zhou, Duan, Wang, Xiao, Duan, Li, Li, Wan, Liu, Song, Zhou, Huang, Wang: "Reconstruction of auto-tissue-engineered lamellar cornea by dynamic culture for transplantation: a rabbit model." in: PLoS ONE, Vol. 9, Issue 4, pp. e93012, (2014) (PubMed).

Li, Rossen, Sinn, Hornick, Steines, Karp, Ernst, Adam, Moninger, Levasseur, Zabner: "Integrin α6β4 identifies human distal lung epithelial progenitor cells with potential as a cell-based therapy for cystic fibrosis lung disease." in: PLoS ONE, Vol. 8, Issue 12, pp. e83624, (2014) (PubMed).

Hsu, Wu, Hung, Lin, Huang, Kuo: "Galectin-1 promotes lung cancer tumor metastasis by potentiating integrin α6β4 and Notch1/Jagged2 signaling pathway." in: Carcinogenesis, Vol. 34, Issue 6, pp. 1370-81, (2013) (PubMed).

Liu, Qin, Liu, Xiang: "Downregulation of integrin β4 decreases the ability of airway epithelial cells to present antigens." in: PLoS ONE, Vol. 7, Issue 4, pp. e32060, (2012) (PubMed).

Synonyme und alternative Namen zu Integrin beta 4

integrin subunit beta 4 (ITGB4), integrin beta 4 (Itgb4), integrin subunit beta 4 (Itgb4), AA407042, C230078O20, CD104

Bezeichner auf Proteinebene für Integrin beta 4

  • integrin beta 4
  • integrin beta-4
  • CD104 antigen
  • GP150
  • integrin beta-4 subunit
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