-
- Applikation
- Inhibition (Inh)
- Verwendungszweck
- HDAC inhibitor
- Produktmerkmale
- Orally active histone deacetylase (HDAC) inhibitor, IC50 = 0.9, 0.9, 1.2 and >20 μM for HDAC1, HDAC2, HDAC3 and HDAC8 respectively. Mediates G1 cell cycle arrest, inhibits proliferation and induces apoptosis in vitro and in vivo. Increases neuroplasticity during memory extinction. Protects beta cells from cytokine-induced apoptosis.
- Reinheit
- >98 %
- Chemical Name
- 4-(Acetylamino)-N-(2-aminophenyl)benzamide
- Formel
- C15H15N3O2
- Löslichkeit
- Soluble in DMSO (up to 25 mg/ml)
-
Geldanamycin
Inh 30562-34-6 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
RadicicolInh 12772-57-5
Geldanamycin- FITCInh 30562-34-6 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
NicotinamideInh 98-92-0 Pyridine-3-carboxylic acid amide
5-AzacytidineInh Cell-permeable 320-67-2 4-Amino-1-ß-D-ribofuranosyl-1,3,5-triazin-2(1H)-one
ResveratrolAct 501-36-0 3,4',5-Trihydroxy-trans-stilbene
PanobinostatInh 404950-80-7 (E)-N-Hydroxy-3-(4-((2-(2-methyl-1H-indol-3-yl)ethylamino)methyl)phenyl)acrylamide
HPA (Hexyl-4-pentynoic acid)Inh Cell-permeable 96017-59-3 2-(2-Propynyl)octanoic acid (racemic)
EX-527Inh Cell-permeable 49843-98-3 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-xarboxamide (racemic)
DaminozideInh 1596-84-5 1-(2,2-Dimethylhydrazide)butanedioic acid
-
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Powder
- Lagerung
- -20 °C
-
- Hintergrund
- PD-123654, N-acetyl-dinaline, GOE-5549,Cytokine,Epigenetics,Apoptosis inducer,Proliferation,Posttranslational modification,Protein deacetylase,Neuroscience,Cell death,Inflammation,Diabetes,Cell cycle,Chromatin
- Molekulargewicht
- 269.30
- CAS-Nummer
- 112522-64-2
-
Sie sind hier:
