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Garcinol

Inh 78824-30-3
Produktnummer ABIN7233254
  • Applikation
    Inhibition (Inh)
    Verwendungszweck
    HAT inhibitor
    Produktmerkmale
    Garcinol is a HAT (histone acetyltransferase) inhibitor (p300 IC50=7μM and PCAF IC50=5μM) both in vitro and in vivo. It potentiates TRAIL-induced apoptosis of cancer cells. Garcinol, independent of the cell type, induces both of the TRAIL receptors, death receptor 4 (DR4) and DR5. Garcinol neither induces the receptors of normal cells nor sensitizes them to TRAIL.
    Reinheit
    >98 %
    Formel
    C38H50O6
    Löslichkeit
    Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Powder
    Lagerung
    -20 °C
  • Hintergrund
    Epigenetics,Posttranslational modification,Acetyltransferase,Cell death,Stem cells,Apoptosis inducer,Chromatin
    Molekulargewicht
    602.80
    CAS-Nummer
    78824-30-3
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