Aktivieren Sie Javascript in Ihrem Browser, um unsere Webseite optimal zu nutzen.

Phenylbutyrate Na

Name: Phenylbutyrate Na
Brand: antibodies-online
SKU: ABIN7233276
Price: 91.54 EUR
Availability: InStock

Inh 1716-12-7 4-Phenylbutyric acid, sodium salt

1 image

Produktnummer ABIN7233276

Datenblatt (PDF)

Applikation

Inhibition (Inh)

Verwendungszweck

HDAC inhibitor

Produktmerkmale

Chemical chaperone for misfolded proteins. Resolves ER stress in neuronal cells by aiding protein folding in the ER. Counteracts impaired glucose homeostasis in a mouse model of type 2 diabetes by preventing islet amyloid formation. Attenuates atherosclerotic progression and stabilizes existing plaques in mouse model of atherosclerosis via inhibition of ER stress. Protects against amyloid β-induced neurotoxicity in a mouse model. Weak histone deacetylase (HDAC) inhibitor which inhibits glioma cell proliferation. Active in vivo.

Reinheit

>98 %

Chemical Name

4-Phenylbutyric acid, sodium salt

Formel

C10H11O2 • Na

Löslichkeit

Soluble in DMSO (up to 4 mg/ml) or in Water (up to 25 mg/ml).
Geldanamycin
Inh 30562-34-6 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate

Radicicol
Inh 12772-57-5

Geldanamycin- FITC
Inh 30562-34-6 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate

Nicotinamide
Inh 98-92-0 Pyridine-3-carboxylic acid amide

5-Azacytidine
Inh Cell-permeable 320-67-2 4-Amino-1-ß-D-ribofuranosyl-1,3,5-triazin-2(1H)-one

Resveratrol
Act 501-36-0 3,4',5-Trihydroxy-trans-stilbene

Panobinostat
Inh 404950-80-7 (E)-N-Hydroxy-3-(4-((2-(2-methyl-1H-indol-3-yl)ethylamino)methyl)phenyl)acrylamide

HPA (Hexyl-4-pentynoic acid)
Inh Cell-permeable 96017-59-3 2-(2-Propynyl)octanoic acid (racemic)

EX-527
Inh Cell-permeable 49843-98-3 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-xarboxamide (racemic)

Daminozide
Inh 1596-84-5 1-(2,2-Dimethylhydrazide)butanedioic acid

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Powder

Lagerung

RT
Hintergrund

4-PB, PBNa,Proliferation,Epigenetics,Posttranslational modification,Cell migration,Protein deacetylase,ER/Golgi,Cellular stress,Cell death,Stem cells,Atherosclerosis,Diabetes,Apoptosis inducer,Neurodegeneration,Chromatin

Molekulargewicht

186.2

CAS-Nummer

1716-12-7