Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

Sirtinol

Inh Cell-permeable 410536-97-9 2-[[(2-Hydroxy-1-naphthalenyl)methylene]amino]-N-(1-phenylethyl)benzamide
Produktnummer ABIN7233291
  • Applikation
    Inhibition (Inh)
    Verwendungszweck
    SIRT inhibitor
    Produktmerkmale
    Inhibitor of sirtuin family enzymes including human SIRT1 (IC50=60μM), human SIRT2 (IC50=58μM), and yeast Sir2 (IC50=48μM) with no inhibition of human HDAC1. Active in vivo and in purified enzyme studies. Cell permeable.
    Reinheit
    >98 %
    Chemical Name
    2-[[(2-Hydroxy-1-naphthalenyl)methylene]amino]-N-(1-phenylethyl)benzamide
    Formel
    C26H22N2O2
    Permeabilität
    Cell-permeable
    Löslichkeit
    Soluble in DMSO (up to 30 mg/ml).
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Powder
    Vorsichtsmaßnahmen
    GHS – Classification
    Skin corrosion/irritation (Category 2), H315
    Serious eye damage/eye irritation (Category 2A), H319
    Specific target organ toxicity-single exposure (Category 3): Respiratory system, H335
    Lagerung
    -20 °C
  • Hintergrund
    Epigenetics,Protein deacetylase,Stem cells,Posttranslational modification,Chromatin
    Molekulargewicht
    394.48
    CAS-Nummer
    410536-97-9
Sie sind hier:
Kundenservice