-
- Applikation
- Inhibition (Inh)
- Verwendungszweck
- HDAC inhibitor
- Produktmerkmale
- Histone deacetylase inhibitor (IC50 = 400μM). Demonstrates neuroprotective, anticancer, and anti-inflammatory activity. Inhibits Aβ production, reduced neuritic plaque formation, and improved memory deficits in Alzheimer's mouse models. Improves stem cell reprogramming efficiency and enables efficient induction of pluripotency without introduction of the oncogene c-Myc. Clinically useful anticonvulsant
- Reinheit
- >98 %
- Chemical Name
- 2-Propylpentanoic acid Na
- Formel
- C8H15O2 Na
- Löslichkeit
- Soluble in Water (up to 50 mg/ml).
-
Geldanamycin
Inh 30562-34-6 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
RadicicolInh 12772-57-5
Geldanamycin- FITCInh 30562-34-6 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
NicotinamideInh 98-92-0 Pyridine-3-carboxylic acid amide
5-AzacytidineInh Cell-permeable 320-67-2 4-Amino-1-ß-D-ribofuranosyl-1,3,5-triazin-2(1H)-one
ResveratrolAct 501-36-0 3,4',5-Trihydroxy-trans-stilbene
PanobinostatInh 404950-80-7 (E)-N-Hydroxy-3-(4-((2-(2-methyl-1H-indol-3-yl)ethylamino)methyl)phenyl)acrylamide
HPA (Hexyl-4-pentynoic acid)Inh Cell-permeable 96017-59-3 2-(2-Propynyl)octanoic acid (racemic)
EX-527Inh Cell-permeable 49843-98-3 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-xarboxamide (racemic)
DaminozideInh 1596-84-5 1-(2,2-Dimethylhydrazide)butanedioic acid
-
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Powder
- Lagerung
- -20 °C
-
- Hintergrund
- Valproic acid,Epigenetics,Autophagy,Protein deacetylase,Cell death,Stem cells,Neuroscience,Neurodegeneration,Posttranslational modification,Chromatin
- Molekulargewicht
- 166.20
- CAS-Nummer
- 1069-66-5
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