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IRF4 Produkte

(Interferon Regulatory Factor 4 (IRF4))
The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6\;14)(p25\;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2010].

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Ausgewählte IRF4 Kategorien

IRF4 Antikörper

High quality antibodies with extensive validation data.

IRF4 ELISA Kits

Reliable ELISA kits for a wide range of species.

IRF4 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene IRF4 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, IF, RNAi
Validierungen
  • (5)
Kat. Nr. ABIN561526
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC (p)
Validierungen
  • (4)
Kat. Nr. ABIN561524
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, ELISA, IHC, IF, ICC
Validierungen
  • (3)
Kat. Nr. ABIN6262655
Menge 100 μL
Datenblatt Datenblatt

Empfohlene IRF4 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6956912
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human, Mouse
Analytical Method Qualitative Cell ELISA
Validierungen
Kat. Nr. ABIN5648116
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN5690899
Menge 96 tests
Datenblatt Datenblatt

Empfohlene IRF4 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1308086
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1308088
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Rat
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7412422
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren IRF4 Produkten

Bakalar, Joffe, Schmid, Son, Podolski, Fletcher: "Size-Dependent Segregation Controls Macrophage Phagocytosis of Antibody-Opsonized Targets." in: Cell, Vol. 174, Issue 1, pp. 131-142.e13, (2018) (PubMed).

Conery, Centore, Neiss, Keller, Joshi, Spillane, Sandy, Hatton, Pardo, Zawadzke, Bommi-Reddy, Gascoigne, Bryant, Mertz, Sims: "Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma." in: eLife, Vol. 5, (2016) (PubMed).

Forero, Moore, Sarkar: "Role of IRF4 in IFN-stimulated gene induction and maintenance of Kaposi sarcoma-associated herpesvirus latency in primary effusion lymphoma cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 191, Issue 3, pp. 1476-85, (2013) (PubMed).

Han, Kraft, Nan, Guo, Chen, Qureshi, Hankinson, Hu, Duffy, Zhao, Martin, Montgomery, Hayward, Thomas, Hoover, Chanock, Hunter: "A genome-wide association study identifies novel alleles associated with hair color and skin pigmentation." in: PLoS genetics, Vol. 4, Issue 5, pp. e1000074, (2008) (PubMed).

Nagel, Pommerenke, Meyer, Kaufmann, MacLeod, Drexler: "NKL homeobox gene MSX1 acts like a tumor suppressor in NK-cell leukemia." in: Oncotarget, Vol. 8, Issue 40, pp. 66815-66832 (PubMed).

Synonyme und alternative Namen zu IRF4

interferon regulatory factor 4 (IRF4), interferon regulatory factor 4 (Irf4), interferon regulatory factor 4a (irf4a), Interferon regulatory factor 4 (irf4), PWWP domain-containing protein MUM1 (LOC612320), PWWP domain-containing protein MUM1 (LOC100068881), AI385587, IRF-4, IRF4, irf4, LSIRF, MUM1, NF-EM5, si:ch73-170d1.2, Spip

Bezeichner auf Proteinebene für IRF4

  • lymphocyte-specific interferon regulatory factor
  • multiple myeloma oncogene 1
  • NF-EM5
  • PU.1 interaction partner
  • Sfpi1/PU.1 interaction partner
  • transcriptional activator PIP
  • interferon regulatory factor 4
  • irf4
  • Interferon regulatory factor 4
  • PWWP domain-containing protein MUM1
  • melanoma associated antigen (mutated) 1
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