IRF6 Produkte
(Interferon Regulatory Factor 6 (IRF6))
Kategorien
This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. The encoded protein may be a transcriptional activator. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. Mutations in this gene are also associated with non-syndromic orofacial cleft type 6. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2011].
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Ausgewählte IRF6 Kategorien
IRF6 Antikörper
High quality antibodies with extensive validation data.
IRF6 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene IRF6 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Dog, Human, Rat
Applikation
WB, IHC, IF, FACS, IHC (p)
Validierungen
- (14)
Kat. Nr.
ABIN1498901
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IF, IP
Validierungen
- (5)
Kat. Nr.
ABIN7101507
Menge
20 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, ELISA
Validierungen
- (4)
Kat. Nr.
ABIN184730
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene IRF6 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6967757
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6205230
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene IRF6 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1308096
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1308094
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7413994
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren IRF6 Produkten
: "IRF6 Regulates Alternative Activation by Suppressing PPARγ in Male Murine Macrophages." in: Endocrinology, Vol. 158, Issue 9, pp. 2837-2847, (2017) (PubMed).: "TGFβ3 regulates periderm removal through ΔNp63 in the developing palate." in: Journal of cellular physiology, Vol. 230, Issue 6, pp. 1212-25, (2015) (PubMed).
: "Interferon regulatory factor 6 differentially regulates Toll-like receptor 2-dependent chemokine gene expression in epithelial cells." in: The Journal of biological chemistry, Vol. 289, Issue 28, pp. 19758-68, (2014) (PubMed).
: "Smad4-Irf6 genetic interaction and TGF?-mediated IRF6 signaling cascade are crucial for palatal fusion in mice." in: Development (Cambridge, England), Vol. 140, Issue 6, pp. 1220-30, (2013) (PubMed).
: "Developmental factor IRF6 exhibits tumor suppressor activity in squamous cell carcinomas." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 33, pp. 13710-5, (2011) (PubMed).
: "A regulatory feedback loop involving p63 and IRF6 links the pathogenesis of 2 genetically different human ectodermal dysplasias." in: The Journal of clinical investigation, Vol. 120, Issue 5, pp. 1570-7, (2010) (PubMed).
: "Interferon regulatory factor 6 promotes cell cycle arrest and is regulated by the proteasome in a cell cycle-dependent manner." in: Molecular and cellular biology, Vol. 28, Issue 7, pp. 2235-43, (2008) (PubMed).
: "Interferon regulatory factor 6 (IRF6) is associated with oral-facial cleft in individuals that originate in South America." in: American journal of medical genetics. Part A, Vol. 143A, Issue 17, pp. 2075-8, (2007) (PubMed).
: "Suggestive linkage to a neighboring region of IRF6 in a cleft lip and palate multiplex family." in: American journal of medical genetics. Part A, Vol. 143A, Issue 22, pp. 2716-21, (2007) (PubMed).
: "Mutations in IRF6 cause Van der Woude and popliteal pterygium syndromes. ..." in: Nature genetics, Vol. 32, Issue 2, pp. 285-9, (2002) (PubMed).
Synonyme und alternative Namen zu IRF6
interferon regulatory factor 6 (IRF6), interferon regulatory factor 6 (irf6), interferon regulatory factor 6 S homeolog (irf6.S), interferon regulatory factor 6 (Irf6), AI876454, DKFZp469E012, E230028I05Rik, IRF6, lps, LPS, mirf6, ofc6, OFC6, pit, PIT, pps, PPS, PPS1, vws, VWS, VWS1, xIRF-6, zgc:63500Bezeichner auf Proteinebene für IRF6
- interferon regulatory factor 6
- interferon regulatory factor 6-like
- IRF-6
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