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ISCU Produkte

(Iron-sulfur cluster assembly enzyme ISCU, mitochondrial (ISCU))

Kategorien

Iron-sulfur (Fe-S) clusters are necessary for several mitochondrial enzymes and other subcellular compartment proteins. They contain sulfur and iron, and are created via several steps that include cysteine desulfurases, iron donors, chaperones, and scaffold proteins. This gene encodes the two isomeric forms, ISCU1 and ISCU2, of the Fe-S cluster scaffold protein. Mutations in this gene have been found in patients with myopathy with severe exercise intolerance and myoglobinuria. [provided by RefSeq, Jul 2008].

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Ausgewählte ISCU Kategorien

ISCU Antikörper

High quality antibodies with extensive validation data.

ISCU Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene ISCU Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, IF
Validierungen
  • (1)
  • (4)
Kat. Nr. ABIN565100
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation WB
Validierungen
  • (5)
  • (2)
Kat. Nr. ABIN1881467
Menge 400 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, IHC, IF, ICC
Validierungen
  • (3)
Kat. Nr. ABIN6262671
Menge 100 μL
Datenblatt Datenblatt

Empfohlene ISCU ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6229179
Menge 96 tests
Datenblatt Datenblatt

Empfohlene ISCU Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1308129
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN6386664
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN2130170
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren ISCU Produkten

Heather, Cole, Tan, Ambrose, Pope, Abd-Jamil, Carter, Dodd, Yeoh, Schofield, Clarke: "Metabolic adaptation to chronic hypoxia in cardiac mitochondria." in: Basic research in cardiology, Vol. 107, Issue 3, pp. 268, (2012) (PubMed).

Okerlund, Kivimäe, Tong, Peng, Ullian, Cheyette: "Dact1 is a postsynaptic protein required for dendrite, spine, and excitatory synapse development in the mouse forebrain." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 12, pp. 4362-8, (2010) (PubMed).

Chan, Zhang, Hemann, Mahoney, Zweier, Loscalzo: "MicroRNA-210 controls mitochondrial metabolism during hypoxia by repressing the iron-sulfur cluster assembly proteins ISCU1/2." in: Cell metabolism, Vol. 10, Issue 4, pp. 273-84, (2009) (PubMed).

Kollberg, Tulinius, Melberg, Darin, Andersen, Holmgren, Oldfors, Holme: "Clinical manifestation and a new ISCU mutation in iron-sulphur cluster deficiency myopathy." in: Brain : a journal of neurology, Vol. 132, Issue Pt 8, pp. 2170-9, (2009) (PubMed).

Huang, Dizin, Cowan: "Mapping iron binding sites on human frataxin: implications for cluster assembly on the ISU Fe-S cluster scaffold protein." in: Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, Vol. 13, Issue 5, pp. 825-36, (2008) (PubMed).

Mochel, Knight, Tong, Hernandez, Ayyad, Taivassalo, Andersen, Singleton, Rouault, Fischbeck, Haller: "Splice mutation in the iron-sulfur cluster scaffold protein ISCU causes myopathy with exercise intolerance." in: American journal of human genetics, Vol. 82, Issue 3, pp. 652-60, (2008) (PubMed).

Synonyme und alternative Namen zu ISCU

iron-sulfur cluster assembly enzyme ISCU, mitochondrial (LOC409130), iron-sulfur cluster assembly enzyme (ISCU), iron-sulfur cluster assembly enzyme a (iscua), iron-sulfur cluster assembly enzyme (Iscu), 2310020H20Rik, AA407971, HML, hnifU, ISU2, NIFU, Nifu, nifun, NIFUN, Nifun, RGD1309562, si:ch211-191d15.3, zC191D15.3

Bezeichner auf Proteinebene für ISCU

  • iron-sulfur cluster assembly enzyme ISCU, mitochondrial
  • iron-sulfur cluster scaffold homolog (E. coli)
  • iron-sulfur cluster assembly enzyme
  • IscU iron-sulfur cluster scaffold homolog (E. coli)
  • NifU-like N-terminal domain containing
  • zC191D15.3 (novel protein with leucine-rich repeat domains)
  • IscU iron-sulfur cluster scaffold homolog
  • iron-sulfur cluster scaffold homolog
  • nifU-like N-terminal domain-containing protein
  • nifU-like protein
  • ISCU2
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