ITPR1 Produkte
(Inositol 1,4,5-Trisphosphate Receptor, Type 1 (ITPR1))
Kategorien
This gene encodes an intracellular receptor for inositol 1,4,5-trisphosphate. Upon stimulation by inositol 1,4,5-trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene. [provided by RefSeq, Nov 2009].
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Ausgewählte ITPR1 Kategorien
ITPR1 Antikörper
High quality antibodies with extensive validation data.
ITPR1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene ITPR1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, IHC (p)
Validierungen
- (1)
- (6)
Kat. Nr.
ABIN3043862
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
IHC, WB, IF
Validierungen
- (5)
Kat. Nr.
ABIN7101690
Menge
20 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, IHC, IF
Validierungen
- (3)
Kat. Nr.
ABIN7156293
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene ITPR1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN1308255
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7422271
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren ITPR1 Produkten
: "Inositol 1,4,5-triphosphate receptor is selectively expressed in cerebellum but not cerebellum-like structures of the elasmobranch fish, Leucoraja erinacea." in: Heliyon, Vol. 5, Issue 1, pp. e01176, (2019) (PubMed).: "BAP1 regulates IP3R3-mediated Ca(2+) flux to mitochondria suppressing cell transformation. ..." in: Nature, Vol. 546, Issue 7659, pp. 549-553, (2017) (PubMed).
: "Absence of the ER Cation Channel TMEM38B/TRIC-B Disrupts Intracellular Calcium Homeostasis and Dysregulates Collagen Synthesis in Recessive Osteogenesis Imperfecta." in: PLoS genetics, Vol. 12, Issue 7, pp. e1006156, (2016) (PubMed).
: "Association of the EF-hand and PH domains of the guanine nucleotide exchange factor SLAT with IP₃ receptor 1 promotes Ca²⁺ signaling in T cells." in: Science signaling, Vol. 7, Issue 345, pp. ra93, (2014) (PubMed).
: "Quantitative proteomic profiling reveals novel region-specific markers in the adult mouse brain." in: Proteomics, Vol. 14, Issue 2-3, pp. 241-61, (2014) (PubMed).
: "Divergent signaling mechanisms for venous versus arterial contraction as revealed by endothelin-1." in: Journal of vascular surgery, (2014) (PubMed).
: "Abolished InsP3R2 function inhibits sweat secretion in both humans and mice." in: The Journal of clinical investigation, Vol. 124, Issue 11, pp. 4773-80, (2014) (PubMed).
: "Microdomains of muscarinic acetylcholine and Ins(1,4,5)P? receptors create 'Ins(1,4,5)P? junctions' and sites of Ca²+ wave initiation in smooth muscle." in: Journal of cell science, Vol. 125, Issue Pt 22, pp. 5315-28, (2013) (PubMed).
: "Fragmented inositol 1,4,5-trisphosphate receptors retain tetrameric architecture and form functional Ca2+ release channels." in: The Journal of biological chemistry, Vol. 288, Issue 16, pp. 11122-34, (2013) (PubMed).
: "Proteomic analysis of primary cultured rat cortical neurons in chemical ischemia." in: Neurochemical research, Vol. 38, Issue 8, pp. 1648-60, (2013) (PubMed).
Synonyme und alternative Namen zu ITPR1
inositol 1,4,5-trisphosphate receptor type 1 (ITPR1), inositol 1,4,5-trisphosphate receptor 1 (Itpr1), inositol 1,4,5-trisphosphate receptor, type 1 (Itpr1), D6Pas2, ENSMUSG00000072853, Gm10429, I145TR, InsP3R, InsP3R1, INSP3R1, Ip3r, IP3R, IP3R1, Itpr-1, opt, P400, Pcp-1, Pcp1, SCA15, SCA16, SCA29Bezeichner auf Proteinebene für ITPR1
- inositol 1,4,5-triphosphate receptor, type 1
- type I inositol triphosphate receptor
- IP3 receptor
- IP3R 1
- InsP3R type I
- InsP>3
- Purkinje cell protein 1
- inositol 1,4,5-triphosphate receptor 1
- inositol 1,4,5-trisphosphate receptor type 1
- inositol 1,4,5-trisphosphate-binding protein P400
- insP3R1
- opisthotonus
- protein PCD-6
- type 1 InsP3 receptor
- type 1 inositol 1,4,5-trisphosphate receptor
- IP-3-R
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