JAK3 Produkte
(Janus Kinase 3 (JAK3))
Kategorien
The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). [provided by RefSeq, Jul 2008].
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Ausgewählte JAK3 Kategorien
JAK3 Antikörper
High quality antibodies with extensive validation data.
JAK3 ELISA Kits
Reliable ELISA kits for a wide range of species.
JAK3 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene JAK3 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, ICC
Validierungen
- (7)
Kat. Nr.
ABIN7439474
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, FACS, ICC
Validierungen
- (1)
- (4)
Kat. Nr.
ABIN969224
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro)
Validierungen
- (1)
- (2)
Kat. Nr.
ABIN681013
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene JAK3 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6968078
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6968077
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6957233
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene JAK3 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1308278
Menge
25 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Insect Cells
Validierungen
Kat. Nr.
ABIN5508976
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Rat
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7398455
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren JAK3 Produkten
: "Combination of gemcitabine and erlotinib inhibits recurrent pancreatic cancer growth in mice via the JAK-STAT pathway." in: Oncology reports, Vol. 39, Issue 3, pp. 1081-1089, (2018) (PubMed).: "Jak3 is involved in CCR7-dependent migration and invasion in metastatic squamous cell carcinoma of the head and neck." in: Oncology letters, Vol. 13, Issue 5, pp. 3191-3197, (2017) (PubMed).
: "Direct regulation of IL-2 by curcumin." in: Biochemical and biophysical research communications, Vol. 495, Issue 1, pp. 300-305, (2017) (PubMed).
: "JAK3 as an Emerging Target for Topical Treatment of Inflammatory Skin Diseases." in: PloS one, Vol. 11, Issue 10, pp. e0164080, (2017) (PubMed).
: "Novel compound heterozygous mutations in a Japanese girl with Janus kinase 3 deficiency." in: Pediatrics international : official journal of the Japan Pediatric Society, Vol. 58, Issue 10, pp. 1076-1080, (2016) (PubMed).
: "MSX3 Switches Microglia Polarization and Protects from Inflammation-Induced Demyelination." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, Issue 16, pp. 6350-65, (2015) (PubMed).
: "Inhibition of STAT3 activation by KT-18618 via the disruption of the interaction between JAK3 and STAT3." in: Biochemical pharmacology, Vol. 89, Issue 1, pp. 62-73, (2014) (PubMed).
: "Jak3 expression and genomic sequence in pediatric acute lymphoblastic leukemia." in: Leukemia & lymphoma, Vol. 43, Issue 12, pp. 2355-62, (2003) (PubMed).
: "MAPKs: new JNK expands the group." in: Trends in biochemical sciences, Vol. 19, Issue 11, pp. 470-3, (1995) (PubMed).
Synonyme und alternative Namen zu JAK3
Janus kinase 3 (JAK3), Janus kinase 3 (Jak3), fae, JAK, JAK-3, JAK3_HUMAN, JAKL, L-JAK, LJAK, RATJAK3, wilBezeichner auf Proteinebene für JAK3
- Janus kinase 3 (a protein tyrosine kinase, leukocyte)
- leukocyte Janus kinase
- tyrosine-protein kinase JAK3
- JAK-3
- Janus kinase 3 protein-tyrosine kinase
- Janus kinase 3, protein-tyrosine kinase
- Janus tyrosine kinase
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