JNK2 Produkte
(Mitogen-Activated Protein Kinase 9 (MAPK9))
Kategorien
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase targets specific transcription factors, and thus mediates immediate-early gene expression in response to various cell stimuli. It is most closely related to MAPK8, both of which are involved in UV radiation induced apoptosis, thought to be related to the cytochrome c-mediated cell death pathway. This gene and MAPK8 are also known as c-Jun N-terminal kinases. This kinase blocks the ubiquitination of tumor suppressor p53, and thus it increases the stability of p53 in nonstressed cells. Studies of this gene's mouse counterpart suggest a key role in T-cell differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Sep 2008].
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Ausgewählte JNK2 Kategorien
JNK2 Antikörper
High quality antibodies with extensive validation data.
JNK2 ELISA Kits
Reliable ELISA kits for a wide range of species.
JNK2 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene JNK2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IF
Validierungen
- (6)
Kat. Nr.
ABIN519243
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IF, PLA
Validierungen
- (6)
Kat. Nr.
ABIN562413
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, FACS
Validierungen
- (5)
Kat. Nr.
ABIN7193450
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene JNK2 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6968649
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6957863
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN5690901
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene JNK2 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
- (2)
Kat. Nr.
ABIN1310315
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7123996
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1310317
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren JNK2 Produkten
: "IL-33 Attenuates Sepsis by Inhibiting IL-17 Receptor Signaling through Upregulation of SOCS3." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 42, Issue 5, pp. 1961-1972, (2017) (PubMed).: "JNK1 protects against glucolipotoxicity-mediated beta-cell apoptosis." in: PLoS ONE, Vol. 9, Issue 1, pp. e87067, (2014) (PubMed).
: "Regulation of mechanical stress-induced MMP-13 and ADAMTS-5 expression by RUNX-2 transcriptional factor in SW1353 chondrocyte-like cells." in: Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society, Vol. 19, Issue 2, pp. 222-32, (2011) (PubMed).
: "In vivo role of p38 mitogen-activated protein kinase in mediating the anti-inflammatory effects of CpG oligodeoxynucleotide in murine asthma." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 169, Issue 10, pp. 5955-61, (2002) (PubMed).
: "A novel mitogen-activated protein kinase is responsive to Raf and mediates growth factor specificity." in: Molecular and cellular biology, Vol. 21, Issue 6, pp. 2235-47, (2001) (PubMed).
: "Involvement of the MAP kinase pathways in induction of GADD45 following UV radiation." in: Experimental cell research, Vol. 269, Issue 1, pp. 64-72, (2001) (PubMed).
: "Diverse functions of JNK signaling and c-Jun in stress response and apoptosis." in: Oncogene, Vol. 18, Issue 45, pp. 6158-62, (1999) (PubMed).
: "Selective interaction of JNK protein kinase isoforms with transcription factors." in: The EMBO journal, Vol. 15, Issue 11, pp. 2760-70, (1996) (PubMed).
: "JNK2 contains a specificity-determining region responsible for efficient c-Jun binding and phosphorylation." in: Genes & development, Vol. 8, Issue 24, pp. 2996-3007, (1995) (PubMed).
: "Signal transduction by tumor necrosis factor mediated by JNK protein kinases." in: Molecular and cellular biology, Vol. 14, Issue 12, pp. 8376-84, (1994) (PubMed).
Synonyme und alternative Namen zu JNK2
mitogen-activated protein kinase 9 (MAPK9), mitogen-activated protein kinase 9 (Mapk9), MAP kinase 9 (MPK9), AI851083, JNK-55, JNK2, JNK2-ALPHA1, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, MAPK9, MAP kinase 9, p54a, p54aSAPK, PRKM9, Prkm9, SAPK, SAPK1aBezeichner auf Proteinebene für JNK2
- mitogen-activated protein kinase 9
- Jun kinase
- MAP kinase 9
- MAPK 9
- c-Jun N-terminal kinase 2
- c-Jun kinase 2
- stress-activated protein kinase 1a
- stress-activated protein kinase JNK2
- JNK/SAPK alpha
- mitogen activated protein kinase 9
- protein kinase, mitogen-activated 9
- SAPK-alpha
- p54-alpha
- stress activated protein kinase alpha II
- janus kinase 2
- c-JUN amino-terminal kinase-2 alpha1
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