KCC2 Produkte
(Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 5 (SLC12A5))
Kategorien
K-Cl cotransporters are proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The protein encoded by this gene is an integral membrane K-Cl cotransporter that can function in either a net efflux or influx pathway, depending on the chemical concentration gradients of potassium and chloride. The encoded protein can act as a homomultimer, or as a heteromultimer with other K-Cl cotransporters, to maintain chloride homeostasis in neurons. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Sep 2008].
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Ausgewählte KCC2 Kategorien
KCC2 Antikörper
High quality antibodies with extensive validation data.
KCC2 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene KCC2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Rat
Applikation
WB, IHC, IP, IF, ICC
Validierungen
- (4)
Kat. Nr.
ABIN1027708
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC (p)
Validierungen
- (3)
Kat. Nr.
ABIN652057
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Mouse, Rat
Applikation
IHC, IF
Validierungen
- (3)
Kat. Nr.
ABIN7075650
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene KCC2 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6210805
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene KCC2 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3118086
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3136773
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren KCC2 Produkten
: "The adipocyte hormone leptin sets the emergence of hippocampal inhibition in mice." in: eLife, Vol. 7, (2019) (PubMed).: "Calpain-2 as a Treatment Target in Prenatal Stress-induced Epileptic Spasms in Infant Rats." in: Experimental neurobiology, Vol. 28, Issue 4, pp. 529-536, (2019) (PubMed).
: "Ionic plasticity and pain: The loss of descending serotonergic fibers after spinal cord injury transforms how GABA affects pain." in: Experimental neurology, Vol. 306, pp. 105-116, (2019) (PubMed).
: "Native KCC2 interactome reveals PACSIN1 as a critical regulator of synaptic inhibition." in: eLife, Vol. 6, (2018) (PubMed).
: "Mutations in SLC12A5 in epilepsy of infancy with migrating focal seizures. ..." in: Nature communications, Vol. 6, pp. 8038, (2015) (PubMed).
: "Neto2-null mice have impaired GABAergic inhibition and are susceptible to seizures." in: Frontiers in cellular neuroscience, Vol. 9, pp. 368, (2015) (PubMed).
: "Down-regulation of KCC2 expression and phosphorylation in motoneurons, and increases the number of in primary afferent projections to motoneurons in mice with post-stroke spasticity." in: PLoS ONE, Vol. 9, Issue 12, pp. e114328, (2015) (PubMed).
: "The developmental switch in GABA polarity is delayed in fragile X mice." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 34, Issue 2, pp. 446-50, (2014) (PubMed).
: "Distribution of neuronal KCC2a and KCC2b isoforms in mouse CNS." in: The Journal of comparative neurology, Vol. 522, Issue 8, pp. 1897-914, (2014) (PubMed).
: "Emergence of motor circuit activity." in: PLoS ONE, Vol. 9, Issue 4, pp. e93836, (2014) (PubMed).
Synonyme und alternative Namen zu KCC2
solute carrier family 12 member 5 (SLC12A5), solute carrier family 12 member 5 (Slc12a5), solute carrier family 12, member 5 (Slc12a5), Kcc2, KCC2, mKIAA1176Bezeichner auf Proteinebene für KCC2
- solute carrier family 12 (potassium/chloride transporter), member 5
- K-Cl cotransporter 2
- electroneutral potassium-chloride cotransporter 2
- furosemide-sensitive K-Cl cotransporter
- neuronal K-Cl cotransporter
- neuronal-specific K-Cl cotransporter
- rKCC2
- solute carrier family 12 member 5
- solute carrier family 12, member 5
- erythroid K-Cl cotransporter 2
- hKCC2
- mKCC2
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