KCNA2 Produkte
(Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 2 (KCNA2))
Kategorien
Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, members of which allow nerve cells to efficiently repolarize following an action potential. The coding region of this gene is intronless, and the gene is clustered with genes KCNA3 and KCNA10 on chromosome 1. [provided by RefSeq, Jul 2008].
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Ausgewählte KCNA2 Kategorien
KCNA2 Antikörper
High quality antibodies with extensive validation data.
KCNA2 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene KCNA2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IF
Validierungen
- (2)
Kat. Nr.
ABIN6142695
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, IHC, IF, ICC
Validierungen
- (3)
Kat. Nr.
ABIN7043517
Menge
25 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
IF
Validierungen
- (1)
Kat. Nr.
ABIN7262100
Menge
200 μL
Datenblatt
Datenblatt
Empfohlene KCNA2 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3112982
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3134601
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (1)
Kat. Nr.
ABIN2724003
Menge
20 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren KCNA2 Produkten
: "Identification of a molecular locus for normalizing dysregulated GABA release from interneurons in the Fragile X brain." in: Molecular psychiatry, (2018) (PubMed).: "Chemical corrector treatment ameliorates increased seizure susceptibility in a mouse model of familial epilepsy." in: Nature medicine, Vol. 21, Issue 1, pp. 19-26, (2015) (PubMed).
: "Use-dependent activation of neuronal Kv1.2 channel complexes." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, Issue 8, pp. 3515-24, (2015) (PubMed).
: "De novo loss- or gain-of-function mutations in KCNA2 cause epileptic encephalopathy. ..." in: Nature genetics, Vol. 47, Issue 4, pp. 393-9, (2015) (PubMed).
: "Sialylation regulates brain structure and function." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 29, Issue 7, pp. 3040-53, (2015) (PubMed).
: "Human Neuroma-in-Continuity Contains Focal Deficits in Myelination." in: Journal of neuropathology and experimental neurology, Vol. 74, Issue 9, pp. 901-911, (2015) (PubMed).
: "Selective down-regulation of KV2.1 function contributes to enhanced arterial tone during diabetes." in: The Journal of biological chemistry, Vol. 290, Issue 12, pp. 7918-29, (2015) (PubMed).
: "BK Channels Localize to the Paranodal Junction and Regulate Action Potentials in Myelinated Axons of Cerebellar Purkinje Cells." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, Issue 18, pp. 7082-94, (2015) (PubMed).
: "Singular localization of sodium channel β4 subunit in unmyelinated fibres and its role in the striatum." in: Nature communications, Vol. 5, pp. 5525, (2014) (PubMed).
: "Ankyrin-G directly binds to kinesin-1 to transport voltage-gated Na+ channels into axons." in: Developmental cell, Vol. 28, Issue 2, pp. 117-31, (2014) (PubMed).
Synonyme und alternative Namen zu KCNA2
potassium voltage-gated channel subfamily A member 2 (KCNA2), potassium channel, voltage gated shaker related subfamily A, member 1 (kcna1), potassium voltage-gated channel, shaker-related subfamily, member 2 (Kcna2), potassium voltage-gated channel subfamily A member 2 (Kcna2), potassium voltage-gated channel subfamily A member 2 (LOC100537815), potassium channel, voltage gated shaker related subfamily A, member 2 S homeolog (kcna2.S), Akr6a4, BK2, ENSMUSG00000074335, Gm10672, HBK5, HK4, HUKIV, k(v)1.2, Kca1-2, KCNA2, kcna2, kcna2-a, KV1.2, Kv1.2, kv1.2, Mk-2, MK2, NGK1, RBK2, XSha2Bezeichner auf Proteinebene für KCNA2
- potassium voltage-gated channel, shaker-related subfamily, member 2
- potassium voltage-gated channel subfamily A member 2-like
- potassium voltage-gated channel subfamily A member 2
- voltage-gated potassium channel Kv1.2
- shaker subfamily potassium channel Kv1.2 alpha subunit
- voltage-gated K(+) channel HuKIV
- voltage-gated potassium channel HBK5
- voltage-gated potassium channel protein Kv1.2
- voltage-gated potassium channel subunit Kv1.2
- MK2
- Potassium (K+) channel protein alpha 2, voltage dependent
- RAK
- RBK2
- RCK5
- potassium voltage gated channel shaker related subfamily member 2
- Kv1.2' potassium channel
- Voltage-gated potassium channel subunit Kv1.2
- potassium voltage-gated channel, shaker-related subfamily, member 2 a
- CSMK1
- delayed rectifier K+ channel
- voltage-dependent K channel
- voltage-gated channel, shaker-related subfamily, member 2
- potassium channel (BGK5)
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