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KCNJ1 Produkte

(Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 (KCNJ1))

Kategorien

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Ausgewählte KCNJ1 Kategorien

KCNJ1 Antikörper

High quality antibodies with extensive validation data.

KCNJ1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene KCNJ1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse, Rat
Applikation WB, IHC
Validierungen
  • (3)
Kat. Nr. ABIN7264605
Menge 200 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation ELISA, IHC, IF
Validierungen
  • (2)
Kat. Nr. ABIN7145017
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation ELISA, WB, IF
Validierungen
  • (2)
Kat. Nr. ABIN7145013
Menge 100 μg
Datenblatt Datenblatt

Empfohlene KCNJ1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6210712
Menge 96 tests
Datenblatt Datenblatt

Empfohlene KCNJ1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1308433
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1780435
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN3098289
Menge 2 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren KCNJ1 Produkten

Zachar, Al-Mashhadi, Dimke, Svenningsen, Jensen, Carlström: "Hydronephrosis is associated with elevated plasmin in urine in pediatric patients and rats and changes in NCC and γ-ENaC abundance in rat kidney." in: American journal of physiology. Renal physiology, Vol. 315, Issue 3, pp. F547-F557, (2018) (PubMed).

Vidal-Petiot, Elvira-Matelot, Mutig, Soukaseum, Baudrie, Wu, Cheval, Huc, Cambillau, Bachmann, Doucet, Jeunemaitre, Hadchouel: "WNK1-related Familial Hyperkalemic Hypertension results from an increased expression of L-WNK1 specifically in the distal nephron." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 35, pp. 14366-71, (2013) (PubMed).

Bhave, Chauder, Liu, Dawson, Kadakia, Nguyen, Lewis, Meiler, Weaver, Satlin, Lindsley, Denton: "Development of a selective small-molecule inhibitor of Kir1.1, the renal outer medullary potassium channel." in: Molecular pharmacology, Vol. 79, Issue 1, pp. 42-50, (2010) (PubMed).

Tobin, Tomaszewski, Braund, Hajat, Raleigh, Palmer, Caulfield, Burton, Samani: "Common variants in genes underlying monogenic hypertension and hypotension and blood pressure in the general population." in: Hypertension, Vol. 51, Issue 6, pp. 1658-64, (2008) (PubMed).

Ji, Foo, ORoak, Zhao, Larson, Simon, Newton-Cheh, State, Levy, Lifton: "Rare independent mutations in renal salt handling genes contribute to blood pressure variation." in: Nature genetics, Vol. 40, Issue 5, pp. 592-9, (2008) (PubMed).

Synonyme und alternative Namen zu KCNJ1

potassium voltage-gated channel subfamily J member 1 (KCNJ1), potassium voltage-gated channel subfamily J member 1 L homeolog (kcnj1.L), potassium voltage-gated channel subfamily J member 1 (kcnj1), potassium voltage-gated channel subfamily J member 1 (Kcnj1), potassium inwardly-rectifying channel, subfamily J, member 1 (Kcnj1), potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 1 (kcnj1a.1), Kcnj, kcnj1, KIR1.1, kir1.1, Kir1.1, ROMK, ROMK1, romk1, Romk2, wu:fl37c05, zgc:63534

Bezeichner auf Proteinebene für KCNJ1

  • ATP-regulated potassium channel ROM-K
  • ATP-sensitive inward rectifier potassium channel 1
  • inward rectifier K(+) channel Kir1.1
  • inwardly rectifying K+ channel
  • potassium channel, inwardly rectifying subfamily J member 1
  • potassium inwardly-rectifying channel, subfamily J, member 1
  • potassium inwardly-rectifying channel J1
  • ATP-sensitive inward rectifier potassium channel 1-like
  • K+ channel protein
  • KAB-1
  • Potassium inwardly-rectifying channel subfamily J
  • kir1.1
  • inwardly rectifying potassium channel ROMK-2
  • LOW QUALITY PROTEIN: ATP-sensitive inward rectifier potassium channel 1
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