KDM2A Produkte
(Lysine (K)-Specific Demethylase 2A (KDM2A))
Kategorien
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains at least six highly degenerated leucine-rich repeats. This family member plays a role in epigenetic silencing. It nucleates at CpG islands and specifically demethylates both mono- and di-methylated lysine-36 of histone H3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012].
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Ausgewählte KDM2A Kategorien
KDM2A Antikörper
High quality antibodies with extensive validation data.
KDM2A Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene KDM2A Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC (p)
Validierungen
- (3)
Kat. Nr.
ABIN387896
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA
Validierungen
- (3)
Kat. Nr.
ABIN7193407
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
ELISA, IHC
Validierungen
- (2)
Kat. Nr.
ABIN7244933
Menge
200 μL
Datenblatt
Datenblatt
Empfohlene KDM2A ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6228355
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene KDM2A Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7123806
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1353718
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3093402
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren KDM2A Produkten
: "HPV16 E7-induced upregulation of KDM2A promotes cervical cancer progression by regulating miR-132-radixin pathway." in: Journal of cellular physiology, (2018) (PubMed).: "Transcriptional repression of histone deacetylase 3 by the histone demethylase KDM2A is coupled to tumorigenicity of lung cancer cells." in: The Journal of biological chemistry, Vol. 289, Issue 11, pp. 7483-96, (2014) (PubMed).
: "KDM2A promotes lung tumorigenesis by epigenetically enhancing ERK1/2 signaling." in: The Journal of clinical investigation, Vol. 123, Issue 12, pp. 5231-46, (2013) (PubMed).
: "Histone demethylation by a family of JmjC domain-containing proteins." in: Nature, Vol. 439, Issue 7078, pp. 811-6, (2006) (PubMed).
: "Nucleolar proteome dynamics." in: Nature, Vol. 433, Issue 7021, pp. 77-83, (2005) (PubMed).
: "Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro." in: DNA research : an international journal for rapid publication of reports on genes and genomes, Vol. 6, Issue 1, pp. 63-70, (1999) (PubMed).
Synonyme und alternative Namen zu KDM2A
lysine demethylase 2A (KDM2A), lysine (K)-specific demethylase 2A (Kdm2a), lysine demethylase 2A (Kdm2a), lysine (K)-specific demethylase 2Aa (kdm2aa), 5530401A10Rik, 100043628, AA589516, AW536790, Cxxc8, CXXC8, fb76b11, Fbl7, FBL7, Fbl11, FBL11, FBXL11, Fbxl11, Gm4560, Jhdm1, JHDM1A, Jhdm1a, KDM2A, lalina, LILINA, wu:fb76b11, wu:fj11c04, zgc:158441, zgc:158606Bezeichner auf Proteinebene für KDM2A
- F-box and leucine-rich repeat protein 11
- jumonji C domain-containing histone demethylase 1A
- lysine-specific demethylase 2A
- F-box protein containing leucine repeats
- F-box/LRR-repeat protein 11
- [Histone-H3]-lysine-36 demethylase 1A
- jmjC domain-containing histone demethylation protein 1A
- lysine (K)-specific demethylase 2A
- CXXC-type zinc finger protein 8
- JmjC domain-containing histone demethylation protein 1B
- lysine (K)-specific demethylase 2B
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