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KDM5B Produkte

(Lysine (K)-Specific Demethylase 5B (KDM5B))

Kategorien

Histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9' or H3 'Lys-27'. Demethylates trimethylated, dimethylated and monomethylated H3 'Lys-4'. Acts as a transcriptional corepressor (By similarity).

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Ausgewählte KDM5B Kategorien

KDM5B Antikörper

High quality antibodies with extensive validation data.

KDM5B Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene KDM5B Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, IF, IHC (p)
Validierungen
  • (3)
  • (8)
Kat. Nr. ABIN1327126
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC, FACS, ICC
Validierungen
  • (4)
Kat. Nr. ABIN5542656
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Rat
Applikation WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro)
Validierungen
  • (3)
Kat. Nr. ABIN762986
Menge 100 μL
Datenblatt Datenblatt

Empfohlene KDM5B Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Insect cells (Sf9)
Validierungen
  • (3)
Kat. Nr. ABIN2669681
Menge 20 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1308520
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source Baculovirus infected Insect Cells, Insect cells (Sf9), Mouse
Validierungen
Kat. Nr. ABIN6700242
Menge 50 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren KDM5B Produkten

Shannan, Matschke, Chauvistré, Vogel, Klein, Meier, Westphal, Bruns, Rauschenberg, Utikal, Forschner, Berking, Terheyden, Dabrowski, Gutzmer, Rafei-Shamsabadi, Meiss, Heinzerling, Zimmer, Livingstone et al.: "Sequence-dependent cross-resistance of combined radiotherapy plus BRAFV600E inhibition in melanoma. ..." in: European journal of cancer (Oxford, England : 1990), Vol. 109, pp. 137-153, (2019) (PubMed).

Vogel, Bordag, Zügner, Trajkovic-Arsic, Chauvistré, Shannan, Váraljai, Horn, Magnes, Siveke, Schadendorf, Roesch: "Targeting the H3K4 demethylase KDM5B reprograms the metabolome and phenotype of melanoma cells." in: The Journal of investigative dermatology, (2019) (PubMed).

Yuan, Liu, Li, Lan, Ma, Li, Kong, Sun, Hou, Hou, Ma, Ren, Zhou, Gao: "Blockade of Immune-Checkpoint B7-H4 and Lysine Demethylase 5B in Esophageal Squamous Cell Carcinoma Confers Protective Immunity against P. gingivalis Infection." in: Cancer immunology research, Vol. 7, Issue 9, pp. 1440-1456, (2019) (PubMed).

Boyle, Fedele, Corbin, Wybacz, Szeto, Lewin, Young, Wong, Fuller, Spillane, Speakman, Donahoe, Pohl, Gyorki, Henderson, Johnstone, Papenfuss, Shackleton: "CD271 Expression on Patient Melanoma Cells Is Unstable and Unlinked to Tumorigenicity." in: Cancer research, Vol. 76, Issue 13, pp. 3965-77, (2016) (PubMed).

Bamodu, Huang, Lee, Wu, Wang, Hsiao, Yeh, Chao: "Aberrant KDM5B expression promotes aggressive breast cancer through MALAT1 overexpression and downregulation of hsa-miR-448." in: BMC cancer, Vol. 16, pp. 160, (2016) (PubMed).

Cui, Song, Hou, Han, Hu, Wu, Chen, Mao: "PLU-1/JARID1B overexpression predicts proliferation properties in head and neck squamous cell carcinoma." in: Oncology reports, Vol. 33, Issue 5, pp. 2454-60, (2015) (PubMed).

Lu, Liu, Li, Xie, Adhiambo, Yang, Ballard, Nakayama, Matusik, Chen: "SKP2 inactivation suppresses prostate tumorigenesis by mediating JARID1B ubiquitination." in: Oncotarget, Vol. 6, Issue 2, pp. 771-88, (2015) (PubMed).

Wang, Mao, Du, He, Han: "Overexpression of JARID1B is associated with poor prognosis and chemotherapy resistance in epithelial ovarian cancer." in: Tumour biology, Vol. 36, Issue 4, pp. 2465-72, (2015) (PubMed).

Klein, Piao, Xi, Rincon-Arano, Rothbart, Peng, Wen, Larson, Zhang, Zheng, Cortazar, Peña, Mangan, Bentley, Strahl, Groudine, Li, Shi, Kutateladze: "The histone-H3K4-specific demethylase KDM5B binds to its substrate and product through distinct PHD fingers." in: Cell reports, Vol. 6, Issue 2, pp. 325-35, (2014) (PubMed).

Stanisz, Saul, Müller, Kappl, Niemeyer, Vogt, Hoth, Roesch, Bogeski: "Inverse regulation of melanoma growth and migration by Orai1/STIM2-dependent calcium entry." in: Pigment cell & melanoma research, Vol. 27, Issue 3, pp. 442-53, (2014) (PubMed).

Synonyme und alternative Namen zu KDM5B

lysine (K)-specific demethylase 5Ba (kdm5ba), lysine (K)-specific demethylase 5Bb (kdm5bb), lysine demethylase 5B (KDM5B), lysine (K)-specific demethylase 5B (Kdm5b), lysine (K)-specific demethylase 5B (KDM5B), lysine demethylase 5B (Kdm5b), 2010009J12Rik, 2210016I17Rik, AW556288, cb264, CT31, D1Ertd202e, id:ibd5050, jarid1b, JARID1B, Jarid1b, jarid1ba, jarid1bb, mKIAA4034, PLU-1, plu1, PLU1, Plu1, PUT1, Rb-Bp2, RBBP2H1A, RGD1565602, wu:fc44h11, wu:fd15c05, zgc:85741

Bezeichner auf Proteinebene für KDM5B

  • jumonji, AT rich interactive domain 1B (Rbp2 like)
  • jumonji, AT rich interactive domain 1Ba (Rbp2 like)
  • histone demethylase JARID1B-B
  • jumonji/ARID domain-containing protein 1B-B
  • lysine-specific demethylase 5B-B
  • putative DNA/chromatin binding motif
  • lysine (K)-specific demethylase 5B
  • Jumonji, AT rich interactive domain 1B (RBP2-like)
  • jumonji, AT rich interactive domain 1B
  • lysine-specific demethylase 5B-like
  • RBP2-H1
  • cancer/testis antigen 31
  • histone demethylase JARID1B
  • jumonji/ARID domain-containing protein 1B
  • lysine-specific demethylase 5B
  • retinoblastoma-binding protein 2 homolog 1
  • retinoblastoma-binding protein 2, homolog 1A
  • putative DNA/chromatin binding motif 1
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