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KEAP1 Produkte

(Kelch-Like ECH-Associated Protein 1 (KEAP1))
This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene. [provided by RefSeq, Jul 2008].

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Ausgewählte KEAP1 Kategorien

KEAP1 Antikörper

High quality antibodies with extensive validation data.

KEAP1 ELISA Kits

Reliable ELISA kits for a wide range of species.

KEAP1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene KEAP1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse
Applikation WB, ELISA, ICC, FACS
Validierungen
  • (2)
  • (5)
Kat. Nr. ABIN1098137
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC, FACS
Validierungen
  • (2)
  • (5)
Kat. Nr. ABIN1098141
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation WB, IHC, IHC (p), FACS
Validierungen
  • (8)
Kat. Nr. ABIN1499016
Menge 100 μL
Datenblatt Datenblatt

Empfohlene KEAP1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (2)
  • (1)
Kat. Nr. ABIN6957270
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6968103
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6975693
Menge 96 tests
Datenblatt Datenblatt

Empfohlene KEAP1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN1308530
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (21)
  • (1)
Kat. Nr. ABIN2724103
Menge 20 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7123669
Menge 50 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren KEAP1 Produkten

Jastrząb, Gęgotek, Skrzydlewska: "Cannabidiol Regulates the Expression of Keratinocyte Proteins Involved in the Inflammation Process through Transcriptional Regulation." in: Cells, Vol. 8, Issue 8, (2020) (PubMed).

Han, Shi, Du, Shi, Zhang, Zheng, Xu, Jiang: "Schisandrin C targets Keap1 and attenuates oxidative stress by activating Nrf2 pathway in Ang II-challenged vascular endothelium." in: Phytotherapy research : PTR, Vol. 33, Issue 3, pp. 779-790, (2019) (PubMed).

Xiang, Ye, Huang, Yu, Chen, Deng, Zhang, Lou, Zhang, Shi, Chen, Zhou: "Brusatol Enhances the Chemotherapy Efficacy of Gemcitabine in Pancreatic Cancer via the Nrf2 Signalling Pathway." in: Oxidative medicine and cellular longevity, Vol. 2018, pp. 2360427, (2018) (PubMed).

Kabel, Alzahrani, Bawazir, Khawtani, Arab: "Targeting the proinflammatory cytokines, oxidative stress, apoptosis and TGF-β1/STAT-3 signaling by irbesartan to ameliorate doxorubicin-induced hepatotoxicity." in: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, Vol. 24, Issue 8, pp. 623-631, (2018) (PubMed).

Kabel, Abd Elmaaboud, Atef, Baali: "Ameliorative potential of linagliptin and/or calcipotriol on bleomycin-induced lung fibrosis: In vivo and in vitro study." in: Environmental toxicology and pharmacology, Vol. 50, pp. 216-226, (2017) (PubMed).

Su, Liu, Wang, Wang, Song, Song: "The electrophilic character of quinones is essential for the suppression of Bach1." in: Toxicology, Vol. 387, pp. 17-26, (2017) (PubMed).

Chen, Li, Fan, Cao, Yao, Xu: "Selenium antagonizes cadmium-induced apoptosis in chicken spleen but not involving Nrf2-regulated antioxidant response." in: Ecotoxicology and environmental safety, Vol. 145, pp. 503-510, (2017) (PubMed).

Kouam, Yuan, Njayou, He, Tsayem, Oladejo, Song, Moundipa, Gao: "Induction of Mkp-1 and Nuclear Translocation of Nrf2 by Limonoids from Khaya grandifoliola C.DC Protect L-02 Hepatocytes against Acetaminophen-Induced Hepatotoxicity." in: Frontiers in pharmacology, Vol. 8, pp. 653, (2017) (PubMed).

Chen, Lin, Liu, Hsu, Lin, Su: "Caveolin-1 Expression Ameliorates Nephrotic Damage in a Rabbit Model of Cholesterol-Induced Hypercholesterolemia." in: PLoS ONE, Vol. 11, Issue 4, pp. e0154210, (2016) (PubMed).

Lutz, Pace, Arnold: "Rotavirus NSP1 Associates with Components of the Cullin RING Ligase Family of E3 Ubiquitin Ligases." in: Journal of virology, Vol. 90, Issue 13, pp. 6036-48, (2016) (PubMed).

Synonyme und alternative Namen zu KEAP1

kelch like ECH associated protein 1 (KEAP1), kelch-like ECH-associated protein 1 (Keap1), Kelch-like ECH-associated protein 1 (Keap1), kelch-like ECH-associated protein 1a (keap1a), kelch like ECH associated protein 1 (keap1), kelch like ECH associated protein 1 L homeolog (keap1.L), kelch like ECH associated protein 1 (Keap1), kelch-like ECH-associated protein 1b (keap1b), fb36f11, INrf2, INRF2, Inrf2, keap1, KEAP1, KLHL19, klhl19, mKIAA0132, wu:fb36f11, zgc:171654

Bezeichner auf Proteinebene für KEAP1

  • cytosolic inhibitor of Nrf2
  • kelch-like family member 19
  • kelch-like protein 19
  • NRF2 cytosolic inhibitor
  • ring canal protein
  • kelch-like ECH-associated protein 1
  • klhl19
  • LOW QUALITY PROTEIN: kelch-like ECH-associated protein 1
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