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KIR2DS1 Produkte

(Killer Cell Immunoglobulin Like Receptor 2DS1 (KIR2DS1))
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules\\\\; thus, KIR proteins are thought to play an important role in regulation of the immune response. [provided by RefSeq, Jul 2008].

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Ausgewählte KIR2DS1 Kategorien

KIR2DS1 Antikörper

High quality antibodies with extensive validation data.

KIR2DS1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene KIR2DS1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation ELISA, WB
Validierungen
  • (1)
Kat. Nr. ABIN657823
Menge 400 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation ELISA
Validierungen
Kat. Nr. ABIN7157510
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation
Validierungen
Kat. Nr. ABIN7157509
Menge 100 μg
Datenblatt Datenblatt

Empfohlene KIR2DS1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
Kat. Nr. ABIN3170493
Menge 2 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN5711333
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Yeast
Validierungen
  • (1)
Kat. Nr. ABIN5714350
Menge 100 μg
Datenblatt Datenblatt

Synonyme und alternative Namen zu KIR2DS1

killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 1 (KIR2DS1), CD158a, CD158H, p50.1

Bezeichner auf Proteinebene für KIR2DS1

  • CD158 antigen-like family member H
  • KIR2DL1-KIR2DS1
  • MHC class I NK cell receptor Eb6 ActI
  • killer cell immunoglobulin-like receptor 2DS1
  • killer cell immunoglobulin-like receptor KIRDS1
  • killer-cell immunoglobulin-like receptor
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