KIR2DS2 Produkte
(Killer Cell Immunoglobulin-Like Receptor 2DS2 (KIR2DS2))
Kategorien
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules\\\\; thus, KIR proteins are thought to play an important role in regulation of the immune response. [provided by RefSeq, Jul 2008].
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Ausgewählte KIR2DS2 Kategorien
KIR2DS2 Antikörper
High quality antibodies with extensive validation data.
KIR2DS2 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene KIR2DS2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
ELISA, IHC, IF
Validierungen
- (3)
Kat. Nr.
ABIN7157511
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, FACS, IHC (p)
Validierungen
- (3)
Kat. Nr.
ABIN651951
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, ICC
Validierungen
- (3)
Kat. Nr.
ABIN1859539
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene KIR2DS2 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7403846
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN3010362
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (1)
Kat. Nr.
ABIN2724252
Menge
20 μg
Datenblatt
Datenblatt
Synonyme und alternative Namen zu KIR2DS2
killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 2 (KIR2DS2), 183ActI, CD158b, CD158J, cl-49, NKAT5Bezeichner auf Proteinebene für KIR2DS2
- 1060P11.9.2
- CD158 antigen-like family member J
- MHC class I NK cell receptor
- NK receptor 183 ActI
- NKAT-5
- killer cell immunoglobulin-like receptor 2DS2
- killer-cell Ig-like receptor
- killer-cell immunoglobulin-like receptor two domains short tail 2 protein
- natural killer associated transcript 5
- natural killer cell inhibitory receptor
- natural killer-associated transcript 5
- p58 KIR
- p58 NK receptor CL-49
- p58 killer cell inhibitory receptor KIR-K7a
- p58 natural killer cell receptor clone CL-49
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