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KIR2DS5 Produkte

(Killer Cell Immunoglobulin-Like Receptor, Two Domains, Short Cytoplasmic Tail, 5 (KIR2DS5))

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Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response.

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Empfohlene KIR2DS5 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation ELISA, IF
Validierungen
  • (1)
Kat. Nr. ABIN7157520
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation WB
Validierungen
  • (1)
Kat. Nr. ABIN6241920
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IF, ICC
Validierungen
  • (1)
Kat. Nr. ABIN6262820
Menge 100 μL
Datenblatt Datenblatt

Empfohlene KIR2DS5 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN3170494
Menge 10 μg
Datenblatt Datenblatt

Synonyme und alternative Namen zu KIR2DS5

killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 5 (KIR2DS5), CD158G, NKAT9

Bezeichner auf Proteinebene für KIR2DS5

  • CD158 antigen-like family member G
  • MHC class I NK cell receptor
  • NKAT-9
  • killer cell immunoglobulin-like receptor 2DS5
  • natural killer cell inhibitory receptor
  • natural killer-associated transcript 9
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