Caspase 1 ELISA Kit

Produktnummer ABIN1168983

Produktdetails Caspase 1 ELISA Kit

Target: Caspase 1 (CASP1)

Reaktivität: Maus

Nachweismethode: Colorimetric

Methodentyp: Sandwich ELISA

Detektionsbereich: 0.15-10 ng/mL

Untere Nachweisgrenze: 0.15 ng/mL

Applikation: ELISA

Proben: Cell Culture Supernatant, Plasma, Serum

Analytische Methode: Quantitative

Spezifität: Detects mouse caspase-1 (proform as well as p10 and p20 domain).

Kreuzreaktivität: Maus

Kreuzreaktivität (Details): Does not detect human caspase-1.

Sensitivität: 33 pg/mL

Produktmerkmale: Standards are full lenght proteins.

Anwendungsinformationen

Plattentyp: Pre-coated

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Handhabung: Avoid freeze/thaw cycles. Plate and reagents should reach room temperature before use.

Lagerung: 4 °C

Informationen zur Lagerung: After standard reconstitution prepare aliquots and store at -20°C.

Haltbarkeit: 12 months

Referenzen für Caspase 1 ELISA Kit (ABIN1168983)

Miyazaki, Mihara, Inata, Sasaki, Tominaga, Yakura, Ishida, Fukushima, Inoue: "Pharmacologic inhibition of IκB kinase activates immediate hypersensitivity reactions in mice." in: The American journal of pathology, Vol. 183, Issue 1, pp. 96-107, (2013) (PubMed).

Details zu Caspase 1

Target: Caspase 1 (CASP1)

Andere Bezeichnung: Caspase-1 (CASP1 Produkte)

Synonyme: ICE ELISA Kit, IL1BC ELISA Kit, P45 ELISA Kit, Il1bc ELISA Kit, Ice ELISA Kit, CASP1 ELISA Kit, CG5370 ELISA Kit, DCP-1 ELISA Kit, DCP1 ELISA Kit, Dcp1 ELISA Kit, Dmel\\CG5370 ELISA Kit, ccp1 ELISA Kit, dcp-1 ELISA Kit, dcp1 ELISA Kit, l(2)01862 ELISA Kit, l(2)02132 ELISA Kit, caspase 1 ELISA Kit, caspase 1, apoptosis-related cysteine peptidase ELISA Kit, caspase 4, apoptosis-related cysteine peptidase ELISA Kit, Death caspase-1 ELISA Kit, caspase-1 ELISA Kit, caspase ELISA Kit, caspase recruitment domain-containing protein 16 ELISA Kit, caspase 4 ELISA Kit, CASP1 ELISA Kit, Casp1 ELISA Kit, CASP4 ELISA Kit, Dcp-1 ELISA Kit, Caspase1 ELISA Kit, LOC5564196 ELISA Kit, LOC451519 ELISA Kit

Hintergrund: Caspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1beta (IL-1beta) and interleukin-18 (IL-18) and induces pyroptotic cell death. Caspase-1 is activated by multiprotein complexes called inflammasomes in response to numerous stimuli that are detected through distinct inflammasomes. NLRC4 responds to cytosolic flagellin, murine NLRP1b responds to anthrax lethal toxin, AIM2 responds to cytosolic DNA and NLRP3/NALP3 responds to a variety of agonists including crystals._x000D__x000D_This Caspase-1 (mouse) ELISA Kit can be used to measure caspase-1 (mouse) in cell culture supernatants. It is a quantitative detection method, alternative to Western blotting to measure caspase-1 secretion.

UniProt: P29452

Pathways: Apoptose, Interferon-gamma Pathway, Positive Regulation of Endopeptidase Activity, Inflammasome