-
- Target Alle Cathepsin D (CTSD) Kits anzeigen
- Cathepsin D (CTSD)
- Nachweismethode
- Fluorometric
- Applikation
- Fluorescence Resonance Energy Transfer Microscopy (FRET)
- Marke
- SensoLyte®
- Produktmerkmale
- The SensoLyte® 390 Cathepsin D Activity Assay Kit uses a Mca/Dnp FRET peptide for measurement of enzyme activity. In the FRET peptide, the fluorescence of Mca is quenched by Dnp. Upon cleavage into two separate fragments by Cathepsin D, the fluorescence of Mca is recovered, and can be monitored at excitation/emission = 330 nm/390 nm.
- Top Product
- Discover our top product CTSD ELISA Kit
-
-
- Kommentare
-
FRET-based Assay Kit
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Handhabung
- Protect Components A and B from light and moisture.
- Lagerung
- -80 °C
- Informationen zur Lagerung
- Store all kit components at -20 °C, except for Component C. Store Component C at -80 °C. Component D can be stored at room temperature for convenience
-
-
Multiple A2E treatments lead to melanization of rod outer segment-challenged ARPE-19 cells." in: Molecular vision, Vol. 20, pp. 285-300, (2014) (PubMed).
: "
-
Multiple A2E treatments lead to melanization of rod outer segment-challenged ARPE-19 cells." in: Molecular vision, Vol. 20, pp. 285-300, (2014) (PubMed).
-
- Target
- Cathepsin D (CTSD)
- Andere Bezeichnung
- Cathepsin D (CTSD Produkte)
- Hintergrund
- Cathepsins are a class of globular lysosomal proteases, playing a vital role in mammalian cellular turnover. They degrade polypeptides and are distinguished by their substrate specificities. Cathepsin D is the lysosomal aspartic proteinase, active in intracellular protein breakdown. It is involved in the pathogenesis of several diseases such as breast cancer and Alzheimer disease.
-