SensoLyte® 520 Cathepsin K Assay Kit

Produktnummer ABIN1882445

Produktdetails

Target: Cathepsin K (CTSK)

Nachweismethode: Fluorometric

Applikation: Fluorescence Resonance Energy Transfer Microscopy (FRET)

Marke: SensoLyte®

Produktmerkmale: The SensoLyte® 520 Cathepsin K Activity Assay Kit uses a QXL™ 520/HiLyte Fluor™ 488 FRET peptide substrate for the measurement of enzyme activity. In the intact FRET peptide, the fluorescence of HiLyte Fluor™ 488 is quenched by QXL™ 520. Upon cleavage of the FRET peptide by the active enzyme, the increase of fluorescence can be continuously monitored at excitation/emission = 490/520 nm. The fluorescent signal from HiLyte Fluor™ 488 is stable at low pH, which is optimal for cathepsin activity. The kit can be used to detect the activity of Cathepsin K enzyme in biological samples and purified enzyme preparations.

Anwendungsinformationen

Kommentare:

FRET-based Assay Kit

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Handhabung: Protect Components A and B from light and moisture.

Lagerung: -80 °C

Informationen zur Lagerung: Store all kit components at -20 °C, except for Component C. Store Component C at -80 °C. Component D can be stored at room temperature for convenience

Antigendetails

Target: Cathepsin K (CTSK)

Andere Bezeichnung: Cathepsin K (CTSK Produkte)

Synonyme: CTS02 Kit, CTSO Kit, CTSO1 Kit, CTSO2 Kit, PKND Kit, PYCD Kit, AI323530 Kit, MMS10-Q Kit, Ms10q Kit, catK Kit, CTSK Kit, wu:fa95f03 Kit, wu:fb08b05 Kit, zgc:110367 Kit, cts02 Kit, ctso Kit, ctso1 Kit, ctso2 Kit, pknd Kit, pycd Kit, OC-2 Kit, catk Kit, cathepsin K Kit, cathepsin K L homeolog Kit, Cathepsin K Kit, CTSK Kit, Ctsk Kit, ctsk Kit, ctsk.L Kit, catk Kit

Hintergrund: Cathepsins are a class of globular lysosomal proteases playing a vital role in mammalian cellular turnover. They degrade polypeptides and are distinguished by their substrate specificities. Cathepsin K is the lysosomal cysteine protease involved in bone remodeling and resorption. It has potential as a drug target in autoimmune diseases and osteoporosis.