Granulin ELISA Kit

Produktnummer ABIN2745482

Maus Granulin ELISA-Kit Colorimetric-Assay zur Quantifizierung von Maus Granulin.

Kurzübersicht für Granulin ELISA Kit (ABIN2745482)

Target: Granulin (GRN)

Reaktivität: Maus

Nachweismethode: Colorimetric

Methodentyp: Sandwich ELISA

Detektionsbereich: 0.125-8 ng/mL

Applikation: ELISA

Proben: Cell Culture Supernatant, Serum

Produktdetails Granulin ELISA Kit

Untere Nachweisgrenze: 0.125 ng/mL

Analytische Methode: Quantitative

Spezifität: Detects mouse progranulin.

Kreuzreaktivität: Maus

Keine Kreuzreaktivität: Human

Kreuzreaktivität (Details): Does not cross-react with human progranulin.

Sensitivität: 60 pg/mL

Produktmerkmale: Progranulin (mouse) ELISA Kit

Anwendungsinformationen

Plattentyp: Pre-coated

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: 4 °C

Informationen zur Lagerung: Short Term Storage: +4°C
Long Term Storage: +4°C
12 months after the day of manufacturing. See expiry date on ELISA Kit box.

Details zu Granulin

Target: Granulin (GRN)

Andere Bezeichnung: Progranulin

Substanzklasse: Viral Protein

Hintergrund: Progranulin (PGRN) is a widely expressed pluripotent growth factor which plays a role in processes such as development, wound repair and inflammation by activating signaling cascades that control cell cycle progression and cell motility. Its function in the central nervous system is of interest, as mutations in the PGRN gene were found in cases of frontotemporal degeneration (FTLD). In addition, PGRN has also been linked to tumorigenesis. New cutting-edge publications have shown that progranulin might be a biomarker not only for FTLD, but also for other types of Alzheimer's disease (AD). This new data even supposes the potential of progranulin to be a biomarker for MCI (Mild Cognitive Impairment), which would be a hallmark in AD research. Additionally, PGRN is described as a new ligand of TNF receptors and a potential therapeutic against inflammatory disease like arthritis.

UniProt: P28798