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LIF ELISA Kit

LIF Reaktivität: Maus AA 24-203 Colorimetric Sandwich ELISA
Produktnummer ABIN5510575
  • Target Alle LIF ELISA Kits anzeigen
    LIF (Leukemia Inhibitory Factor (LIF))
    Bindungsspezifität
    AA 24-203
    Reaktivität
    • 6
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Maus
    Nachweismethode
    Colorimetric
    Methodentyp
    Sandwich ELISA
    Applikation
    ELISA
    Verwendungszweck
    Sandwich High Sensitivity ELISA kit for Quantitative Detection of Mouse LIF
    Marke
    PicoKine™
    Analytische Methode
    Quantitative
    Spezifität
    Expression system for standard: E.coli
    Immunogen sequence: S24-F203
    Kreuzreaktivität (Details)
    There is no detectable cross-reactivity with other relevant proteins.
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  • Plattentyp
    Pre-coated
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
    Haltbarkeit
    12 months
  • Target Alle LIF ELISA Kits anzeigen
    LIF (Leukemia Inhibitory Factor (LIF))
    Andere Bezeichnung
    Lif (LIF Produkte)
    Synonyme
    CDF ELISA Kit, DIA ELISA Kit, HILDA ELISA Kit, MLPLI ELISA Kit, LIF, interleukin 6 family cytokine ELISA Kit, leukemia inhibitory factor ELISA Kit, LIF ELISA Kit, Lif ELISA Kit
    Hintergrund

    Protein Function: LIF has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes.

    Background: Leukemia inhibitory factor, or LIF, is an interleukin 6 class cytokine that affects cell growth by inhibiting differentiation. When LIF levels drop, the cells differentiate. The LIF was mapped gene to 22q11-q12.2 by Southern analysis of a series of mouse/human somatic cell hybrids and by in situ hybridization to the chromosomes of 2 normal males and some individuals with chromosomal rearrangements. The gene maps between the Philadelphia translocation BCR1 and the breakpoint of the translocation in cell line GM2324 at 22q12.2. LIF derives its name from its ability to induce the terminal differentiation of myeloid leukemic cells, thus preventing their continued growth. Other properties attributed to the cytokine include: the growth promotion and cell differentiation of different types of target cells, influence on bone metabolism, cachexia, neural development, embryogenesis and inflammation.

    Synonyms: Leukemia inhibitory factor,LIF,Differentiation-stimulating factor,D factor,Lif,

    Full Gene Name: Leukemia inhibitory factor

    Cellular Localisation: Secreted.
    UniProt
    P09056
    Pathways
    JAK-STAT Signalweg, Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Stem Cell Maintenance, Growth Factor Binding
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