CCL27 ELISA Kit

Produktnummer ABIN5510583

Produktdetails CCL27 ELISA Kit

Target: CCL27 (Chemokine (C-C Motif) Ligand 27 (CCL27))

Bindungsspezifität: AA 26-120

Reaktivität: Maus

Nachweismethode: Colorimetric

Methodentyp: Sandwich ELISA

Applikation: ELISA

Verwendungszweck: Sandwich High Sensitivity ELISA kit for Quantitative Detection of Mouse CCL27/CTACK

Marke: PicoKine™

Analytische Methode: Quantitative

Spezifität: Expression system for standard: E.coli
Immunogen sequence: L26-N120

Kreuzreaktivität (Details): There is no detectable cross-reactivity with other relevant proteins.

Produktmerkmale:

Tissue Specificity: Isoform 1 is predominantly expressed in placenta and weakly in skin. Isoform 2 is predominantly expressed in testes and brain, weakly in kidney and liver and even lower in heart and muscle. Low expression of both isoforms in other tissues.

Anwendungsinformationen

Plattentyp: Pre-coated

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

Haltbarkeit: 12 months

Details zu CCL27

Target: CCL27 (Chemokine (C-C Motif) Ligand 27 (CCL27))

Andere Bezeichnung: Ccl27 (CCL27 Produkte)

Hintergrund:

Protein Function: Chemotactic factor that attracts skin-associated memory T-lymphocytes. May play a role in mediating homing of lymphocytes to cutaneous sites. May play a role in cell migration during embryogenesis. Nuclear forms may facilitate cellular migration by inducing cytoskeletal relaxation. Binds to CCR10.

Background: Chemokine (C-C motif) ligand 27 (CCL27) is a small cytokine belonging to the CC chemokine family, it is also known under the names IL-11 R-alpha-locus chemokine (ILC), Skinkine, ESkine and Cutaneous T-cell-attracting chemokine (CTACK). The human gene is mapped to 9p13.3. CCL27 is associated with homing of memory T lymphocytes to the skin, and plays a role in T cell-mediatedinflammation of the skin. And CCL27 is expressed in numerous tissues, including gonads, thymus, placenta and skin. It elicits its chemotacticeffects by binding to the chemokine receptor CCR10.

Synonyms: C-C motif chemokine 27,CC chemokine ILC,Cutaneous T-cell-attracting chemokine,CTACK,ESkine,IL-11 R-alpha-locus chemokine,ALP,mILC,Skinkine,Small-inducible cytokine A27,Ccl27,Ilc, Scya27,

Full Gene Name: C-C motif chemokine 27

Cellular Localisation: Isoform 1: Secreted . Nucleus . May also be nuclear when following receptor (CCR10)-mediated internalization..

UniProt: Q9Z1X0