Sclerostin ELISA Kit
Kurzübersicht für Sclerostin ELISA Kit (ABIN5510605)
Target
Alle Sclerostin (SOST) ELISA Kits anzeigenBindungsspezifität
Reaktivität
Nachweismethode
Methodentyp
Applikation
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Verwendungszweck
- Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human Sclerostin/SOST
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Marke
- PicoKine™
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Analytische Methode
- Quantitative
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Spezifität
- Expression system for standard: NSO, Immunogen sequence: Q24-Y213
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Kreuzreaktivität (Details)
- There is no detectable cross-reactivity with other relevant proteins.
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Produktmerkmale
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Tissue Specificity: Widely expressed at low levels with highest levels in bone, cartilage, kidney, liver, bone marrow and primary osteoblasts differentiated for 21 days. Detected in the subendothelial layer of the aortic intima (at protein level). .
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Sclerostin (SOST) ELISA Kit
SOST Reaktivität: Human Colorimetric Sandwich ELISA 0.31 ng/mL - 20 ng/mL Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate
Sclerostin (SOST) ELISA KitSOST Reaktivität: Maus Colorimetric Sandwich ELISA 6.25 pg/mL - 400 pg/mL Plasma, Serum, Tissue Homogenate
Sclerostin (SOST) ELISA KitSOST Reaktivität: Ratte Colorimetric Sandwich ELISA 78 pg/mL - 5000 pg/mL Plasma, Serum, Tissue Homogenate
Sclerostin (SOST) ELISA KitSOST Reaktivität: Ratte Colorimetric Sandwich ELISA 31.25 pg/mL - 2000 pg/mL Cell Culture Supernatant, Plasma, Serum
Sclerostin (SOST) ELISA KitSOST Reaktivität: Maus AA 24-211 Colorimetric Sandwich ELISA 15.6-1000 pg/mL Cell Culture Supernatant, Plasma (EDTA), Plasma (heparin), Serum
Sclerostin (SOST) ELISA KitSOST Reaktivität: Ratte AA 29-213 Colorimetric Sandwich ELISA
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Plattentyp
- Pre-coated
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
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Haltbarkeit
- 12 months
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- Sclerostin (SOST)
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Andere Bezeichnung
- SOST
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Hintergrund
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Protein Function: Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation. .
Background: Sclerostin is a protein that in humans is encoded by the SOST gene. It is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Additionally, Sclerostin is produced by the osteocyte and has anti-anabolic effects on bone formation. The SOST gene maps to chromosome 17q12-q21.
Synonyms: Sclerostin,SOST,UNQ2976/PRO7455/PRO7476,
Full Gene Name: Sclerostin
Cellular Localisation: Secreted, extracellular space, extracellular matrix. -
UniProt
- Q9BQB4
Target Alle Sclerostin (SOST) ELISA Kits anzeigen
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