TGFB3 ELISA Kit

Produktnummer ABIN5510616

Produktdetails TGFB3 ELISA Kit

Target: TGFB3 (Transforming Growth Factor, beta 3 (TGFB3))

Bindungsspezifität: AA 301-412

Reaktivität: Hund

Nachweismethode: Colorimetric

Methodentyp: Sandwich ELISA

Applikation: ELISA

Verwendungszweck: Sandwich High Sensitivity ELISA kit for Quantitative Detection of activated Dog Caninea TGF-beta 3

Marke: PicoKine™

Analytische Methode: Quantitative

Spezifität: Expression system for standard: sf21
Immunogen sequence: A301-S412

Kreuzreaktivität (Details): There is no detectable cross-reactivity with other relevant proteins.

Produktmerkmale:

Sequence similarities: Belongs to the TGF-beta family.

Anwendungsinformationen

Plattentyp: Pre-coated

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4 °C for 6 months, at -20 °C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

Haltbarkeit: 12 months

Details zu TGFB3

Target: TGFB3 (Transforming Growth Factor, beta 3 (TGFB3))

Andere Bezeichnung: TGFB3 (TGFB3 Produkte)

Synonyme: TGFB3 ELISA Kit, ARVD ELISA Kit, TGF-beta3 ELISA Kit, Tgfb-3 ELISA Kit, TGF-B3 ELISA Kit, TGFbeta3 ELISA Kit, wu:fc78g09 ELISA Kit, zgc:92058 ELISA Kit, transforming growth factor beta 3 ELISA Kit, transforming growth factor, beta 3 ELISA Kit, TGFB3 ELISA Kit, Tgfb3 ELISA Kit, tgfb3 ELISA Kit

Hintergrund:

Protein Function: Involved in embryogenesis and cell differentiation.

Background: Transforming growth factor beta 3(TGF-beta 3) is a type of protein, known as a cytokine, which is involved in cell differentiation, embryogenesis and development. It belongs to a large family of cytokines called the Transforming growth factor beta superfamily. TGF-beta 3 is believed to regulate molecules involved in cellular adhesion and extracellular matrix(ECM) formation during the process of palate development. Without TGF-beta 3, mammals develop a deformity known as acleft palate. This is caused by failure of epithelial cells in both sides of the developing palate to fuse. TGF-beta 3 also plays an essential role in controlling the development of lungs in mammals, by also regulating cell adhesion and ECM formation in this tissue, and controls wound healing by regulating the movements of epidermal and dermal cells in injured skin. TGF-beta 3 activated Lef1 in the absence of beta-catenin(CTNNB1) via nuclear phospho-Smad2 and Smad4.

Synonyms: Transforming growth factor beta-3,TGF-beta-3,Latency-associated peptide,LAP,TGFB3,

Full Gene Name: Transforming growth factor beta-3

Cellular Localisation: Secreted.

UniProt: P10600

Pathways: Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus