CXCL14 ELISA Kit

Produktnummer ABIN5510624

Produktdetails CXCL14 ELISA Kit

Target: CXCL14 (Chemokine (C-X-C Motif) Ligand 14 (CXCL14))

Bindungsspezifität: AA 35-111

Reaktivität: Hamster

Nachweismethode: Colorimetric

Methodentyp: Sandwich ELISA

Applikation: ELISA

Verwendungszweck: Sandwich High Sensitivity ELISA kit for Quantitative Detection of Chinese hamster CXCL14

Marke: PicoKine™

Analytische Methode: Quantitative

Spezifität: Expression system for standard: E.coli
Immunogen sequence: S35-E111

Kreuzreaktivität (Details): There is no detectable cross-reactivity with other relevant proteins.

Produktmerkmale:

Sequence similarities: Belongs to the intercrine alpha (chemokine CxC) family.

Tissue Specificity: Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Highly expressed in normal tissue without inflammatory stimuli and infrequently expressed in cancer cell lines. Weakly expressed in monocyte- derived dendritic cells. Not detected in lung or unstimulated peripheral blood lymphocytes. .

Anwendungsinformationen

Plattentyp: Pre-coated

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4 °C for 6 months, at -20 °C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

Haltbarkeit: 12 months

Details zu CXCL14

Target: CXCL14 (Chemokine (C-X-C Motif) Ligand 14 (CXCL14))

Andere Bezeichnung: CXCL14 (CXCL14 Produkte)

Synonyme: BMAC ELISA Kit, BRAK ELISA Kit, KEC ELISA Kit, KS1 ELISA Kit, MIP-2g ELISA Kit, MIP2G ELISA Kit, NJAC ELISA Kit, SCYB14 ELISA Kit, 1110031L23Rik ELISA Kit, 1200006I23Rik ELISA Kit, AI414372 ELISA Kit, Kec ELISA Kit, MIP2gamma ELISA Kit, Scyb14 ELISA Kit, bolekine ELISA Kit, scyba ELISA Kit, fb67g04 ELISA Kit, wu:fb67g04 ELISA Kit, JSC ELISA Kit, bmac ELISA Kit, brak ELISA Kit, kec ELISA Kit, ks1 ELISA Kit, mip-2g ELISA Kit, mip2g ELISA Kit, njac ELISA Kit, scyb14 ELISA Kit, CXCL14 ELISA Kit, DKFZp469J175 ELISA Kit, C-X-C motif chemokine ligand 14 ELISA Kit, chemokine (C-X-C motif) ligand 14 ELISA Kit, chemokine (C-X-C motif) ligand 14 L homeolog ELISA Kit, CXCL14 ELISA Kit, Cxcl14 ELISA Kit, cxcl14 ELISA Kit, cxcl14.L ELISA Kit

Hintergrund:

Protein Function: Potent chemoattractant for neutrophils, and weaker for dendritic cells. Not chemotactic for T-cells, B-cells, monocytes, natural killer cells or granulocytes. Does not inhibit proliferation of myeloid progenitors in colony formation assays. .

Background: Chemokine(C-X-C motif) ligand 14(CXCL14) is a small cytokine belonging to the CXC chemokine family that is also known as BRAK(for breast and kidney-expressed chemokine). This gene is mapped to 5q31.1. CXCL14 is constitutively expressed at high levels in many normal tissues, it has been found that fibroblasts are the primary source of CXCL14 and that CXCL14 is involved in the homeostasis of monocyte-derived macrophages rather than in inflammation. It is also a potent chemoattractant and activator of dendritic cells, is implicated in homing of these cells, and can stimulate the migration of activated NK cells. CXCL14 also inhibits angiogenesis, possibly as a result of its ability to block endothelial cell chemotaxis. In addition to it, CXCL14 is a potent chemokine for immature DCs, with a chemoattractive activity comparable to bacterial fMLP and MIP1A.

Synonyms: C-X-C motif chemokine 14,Chemokine BRAK,MIP-2G,Small-inducible cytokine B14,CXCL14,MIP2G, NJAC, SCYB14,PSEC0212, UNQ240/PRO273,

Full Gene Name: C-X-C motif chemokine 14

Cellular Localisation: Secreted.

UniProt: O95715

Pathways: Autophagie