Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

Epiregulin ELISA Kit

EREG Reaktivität: Affe AA 60-108 Colorimetric Sandwich ELISA
Produktnummer ABIN5510631
  • Target Alle Epiregulin (EREG) ELISA Kits anzeigen
    Epiregulin (EREG)
    Bindungsspezifität
    AA 60-108
    Reaktivität
    • 9
    • 8
    • 4
    • 1
    Affe
    Nachweismethode
    Colorimetric
    Methodentyp
    Sandwich ELISA
    Applikation
    ELISA
    Verwendungszweck
    Sandwich High Sensitivity ELISA kit for Quantitative Detection of monkey primate Epiregulin
    Marke
    PicoKine™
    Analytische Methode
    Quantitative
    Spezifität
    E.coli, V60-L108
    Kreuzreaktivität (Details)
    There is no detectable cross-reactivity with other relevant proteins.
    Produktmerkmale

    Tissue Specificity: In normal adults, expressed predominantly in the placenta and peripheral blood leukocytes. High levels were detected in carcinomas of the bladder, lung, kidney and colon. .

    Featured
    Zu unserem meistverkauften EREG ELISA Kit
    Top Product
    Discover our top product EREG ELISA Kit
  • Plattentyp
    Pre-coated
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
    Haltbarkeit
    12 months
  • Target Alle Epiregulin (EREG) ELISA Kits anzeigen
    Epiregulin (EREG)
    Andere Bezeichnung
    EREG (EREG Produkte)
    Hintergrund

    Protein Function: Ligand of the EGF receptor/EGFR and ERBB4. Stimulates EGFR and ERBB4 tyrosine phosphorylation (PubMed:9419975). Contributes to inflammation, wound healing, tissue repair, and oocyte maturation by regulating angiogenesis and vascular remodeling and by stimulating cell proliferation (PubMed:24631357). .

    Background: Epiregulin (EPR) is a protein that in humans is encoded by the EREG gene. It is a member of the epidermal growth factor family. Epiregulin can function as a ligand of epidermal growth factor receptor (EGFR), as well as a ligand of most members of the ERBB (v-erb-b2 oncogene homolog) family of tyrosine-kinase receptors. The secondary structure at the C-terminus epiregulin is different from other epidermal growth factor family ligands because of the lack of hydrogen bonds. The structural difference at the C-terminus may provide an explanation for the reduced binding affinity of epiregulin to the ERBB receptors.

    Synonyms: Proepiregulin,Epiregulin,EPR,EREG,

    Full Gene Name: Proepiregulin

    Cellular Localisation: Epiregulin: Secreted, extracellular space.
    UniProt
    O14944
    Pathways
    RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Muscle Cell Differentiation
Sie sind hier:
Kundenservice