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- Target Alle KREMEN1 ELISA Kits anzeigen
- KREMEN1 (Kringle Containing Transmembrane Protein 1 (KREMEN1))
- Bindungsspezifität
- AA 20-395
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Reaktivität
- Maus
- Nachweismethode
- Colorimetric
- Methodentyp
- Sandwich ELISA
- Applikation
- ELISA
- Verwendungszweck
- Sandwich High Sensitivity ELISA kit for Quantitative Detection of Mouse Kremen-1
- Marke
- PicoKine™
- Analytische Methode
- Quantitative
- Spezifität
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Expression system for standard: NSO
Immunogen sequence: A20-G395 - Kreuzreaktivität (Details)
- There is no detectable cross-reactivity with other relevant proteins.
- Produktmerkmale
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Tissue Specificity: In the adult, widely expressed with high levels in heart, lung, kidney, skeletal muscle and testis. .
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- Plattentyp
- Pre-coated
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
- Haltbarkeit
- 12 months
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- Target Alle KREMEN1 ELISA Kits anzeigen
- KREMEN1 (Kringle Containing Transmembrane Protein 1 (KREMEN1))
- Andere Bezeichnung
- Kremen1 (KREMEN1 Produkte)
- Hintergrund
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Protein Function: Receptor for Dickkopf protein. Cooperates with Dickkopf to block Wnt/beta-catenin signaling (By similarity). .
Background: Kremen protein 1 is a protein that in humans is encoded by the KREMEN1 gene. This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.
Synonyms: Kremen protein 1,Dickkopf receptor,Kringle domain-containing transmembrane protein 1,Kringle-containing protein marking the eye and the nose,Kremen1,Kremen,
Full Gene Name: Kremen protein 1
Cellular Localisation: Membrane, Single-pass type I membrane protein. - UniProt
- Q99N43
- Pathways
- WNT Signalweg
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