Kallikrein 1 ELISA Kit

Produktnummer ABIN5510741

Produktdetails Kallikrein 1 ELISA Kit

Target: Kallikrein 1 (KLK1)

Bindungsspezifität: AA 25-261

Reaktivität: Maus

Nachweismethode: Colorimetric

Methodentyp: Sandwich ELISA

Applikation: ELISA

Verwendungszweck: Sandwich High Sensitivity ELISA kit for Quantitative Detection of Mouse KLK1

Marke: PicoKine™

Analytische Methode: Quantitative

Spezifität: Expression system for standard: NSO, Immunogen sequence: I25-D261

Kreuzreaktivität (Details): There is no detectable cross-reactivity with other relevant proteins.

Anwendungsinformationen

Plattentyp: Pre-coated

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

Haltbarkeit: 12 months

Details zu Kallikrein 1

Target: Kallikrein 1 (KLK1)

Andere Bezeichnung: Klk1 (KLK1 Produkte)

Hintergrund:

Protein Function: Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin.

Background: Kallikrein-1, also known as tissue kallikrein, is a protein that in humans is encoded by the KLK1 gene. This serine protease generates Lys-bradykinin by specific proteolysis of kininogen-1. KLK1 is a member of the peptidase S1 family. Its gene is mapped to 19q13.3. In all, it has got 262-amino acids which contain a putative signal peptide, followed by a short activating peptide and the protease domain. The protein is mainly found in kidney, pancreas, and salivary gland, showing a unique pattern of tissue-specific expression relative to other members of the family. KLK1 is implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers.

Synonyms: Kallikrein-1,3.4.21.35,Glandular kallikrein K1,KAL-B,Renal kallikrein,Tissue kallikrein-6,mGK-6,Klk1,Klk-6, Klk6,

Full Gene Name: Kallikrein-1

UniProt: P15947

Pathways: Komplementsystem