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GDF2 ELISA Kit

GDF2 Reaktivität: Maus AA 319-428 Colorimetric Sandwich ELISA
Produktnummer ABIN5510748
  • Target Alle GDF2 ELISA Kits anzeigen
    GDF2 (Growth Differentiation Factor 2 (GDF2))
    Bindungsspezifität
    AA 319-428
    Reaktivität
    • 9
    • 7
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Maus
    Nachweismethode
    Colorimetric
    Methodentyp
    Sandwich ELISA
    Applikation
    ELISA
    Verwendungszweck
    Sandwich High Sensitivity ELISA kit for Quantitative Detection of Mouse BMP-9
    Marke
    PicoKine™
    Analytische Methode
    Quantitative
    Spezifität
    Expression system for standard: CHO, Immunogen sequence: S319-R428
    Kreuzreaktivität (Details)
    There is no detectable cross-reactivity with other relevant proteins.
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  • Plattentyp
    Pre-coated
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
    Haltbarkeit
    12 months
  • Target Alle GDF2 ELISA Kits anzeigen
    GDF2 (Growth Differentiation Factor 2 (GDF2))
    Andere Bezeichnung
    Gdf2 (GDF2 Produkte)
    Synonyme
    bmp9 ELISA Kit, BMP-9 ELISA Kit, BMP9 ELISA Kit, Bmp9 ELISA Kit, DSL1 ELISA Kit, growth differentiation factor 2 ELISA Kit, gdf2 ELISA Kit, GDF2 ELISA Kit, Gdf2 ELISA Kit
    Hintergrund

    Protein Function: Potent circulating inhibitor of angiogenesis. Could be involved in bone formation. Signals through the type I activin receptor ACVRL1 but not other Alks. Signaling through SMAD1 in endothelial cells requires TGF-beta coreceptor endoglin/ENG.

    Background: Growth differentiation factor 2 (GDF2) also known as bone morphogenetic protein (BMP)-9 is a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates cartilage and bone development, angiogenesis and differentiation of cholinergic central nervous system neurons. Homozygous null mice exhibit malformations of the vasculature and skeleton.

    Synonyms: Growth/differentiation factor 2, GDF-2, Bone morphogenetic protein 9, BMP-9, Gdf2, Bmp9,

    Full Gene Name: growth differentiation factor 2

    Cellular Localisation: Secreted.
    UniProt
    Q9WV56
    Pathways
    Transition Metal Ion Homeostasis
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