IL-19 ELISA Kit

Produktnummer ABIN5692212

Produktdetails IL-19 ELISA Kit

Target: IL-19 (IL19) (Interleukin 19 (IL19))

Bindungsspezifität: AA 25-177

Reaktivität: Human

Nachweismethode: Colorimetric

Methodentyp: Sandwich ELISA

Detektionsbereich: 31.2 pg/mL - 2000 pg/mL

Untere Nachweisgrenze: 31.2 pg/mL

Applikation: ELISA

Verwendungszweck: Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human IL-19. 96wells/kit, with removable strips.

Marke: PicoKine™

Proben: Cell Culture Supernatant, Plasma (EDTA - heparin), Serum, Urine

Analytische Methode: Quantitative

Spezifität: Expression system for standard: E.coli, Immunogen sequence: L25-A177

Sensitivität: < 10 pg/mL

Bestandteile: 96-well plate precoated with antibody
lyophilized recombinant standard
biotinylated antibody (dilution 1:100)
Avidin-Biotin-Peroxidase Complex(ABC)(dilution 1:100)
Sample diluent buffer
Antibody diluent buffer
ABC diluent buffer
TMB color developing agent
TMB stop solution
Adhesive cover

Anwendungsinformationen

Testdauer: 25 min

Plattentyp: Pre-coated

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

Haltbarkeit: 12 months

Details zu IL-19

Target: IL-19 (IL19) (Interleukin 19 (IL19))

Andere Bezeichnung: IL19 (IL19 Produkte)

Hintergrund:

Synonyms: Interleukin-19, IL-19, Melanoma differentiation-associated protein-like protein, NG.1, IL19, ZMDA1

Background: Interleukin 19 (IL19) is a protein that in humans is encoded by the IL19 gene. The protein encoded by this gene is a cytokine that belongs to the IL-10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the interleukin-20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described.

Cellular Localisation: Secreted.

UniProt: Q9UHD0