IL6RA ELISA Kit

Produktnummer ABIN6719752

Produktdetails IL6RA ELISA Kit

Target: IL6RA (Interleukin 6 Receptor, alpha (IL6RA))

Reaktivität: Human

Nachweismethode: Colorimetric

Methodentyp: Sandwich ELISA

Detektionsbereich: 31.2 pg/mL - 2000 pg/mL

Untere Nachweisgrenze: 31.2 pg/mL

Applikation: ELISA

Verwendungszweck: Sandwich ELISA for Quantitative Detection of Antigen

Proben: Cell Culture Supernatant, Plasma (EDTA - heparin - citrate), Serum

Analytische Methode: Quantitative

Produktmerkmale:

Synonyms: CD126, CD126 antigen, Gp80, IL 6R 1, IL 6R alpha, IL-6 receptor subunit alpha, IL-6R 1, IL-6R subunit alpha, IL-6R-1, IL-6R-alpha, IL-6RA, Il6r, IL6R1, IL6RA, IL6RA_HUMAN, IL6Ralpha, Interleukin 6 receptor, Interleukin 6 receptor alpha chain, Interleukin-6 receptor subunit alpha, Membrane glycoprotein 80, MGC104991, OTTHUMP00000034320

Background: IL6R alpha(IL6RA) also known as CD126 or IL6R, is a type I cytokine receptor. The IL6 receptor is a protein complex consisting of a IL-6 receptor subunit(IL6R) and interleukin 6 signal transducer Glycoprotein 130. IL6R also denotes the human gene encoding this subunit. Alternatively spliced transcript variants encoding distinct isoforms have been reported. IL6R subunit is also shared by many other cytokines. Interleukin-6 receptor has been shown to interact with Interleukin 6 and Ciliary neurotrophic factor. Ligand binding did not appear to affect IL6R dimerization status. IL6R dimerization occurs both on the cell surface and in solution.

Gene Name: IL6R

Production: Natural and recombinant human IL-6R alpha. There is no detectable cross-reactivity with other relevant proteins.

Standard: Expression system for standard: sf21, Immunogen sequence: L20-D358

Anwendungsinformationen

Applikationshinweise:

Application Note: Useful in Sandwich ELISA for Quantitative Detection of Antigen. Aliquot 0.1 mL per well of the 2000pg/mL, 1000pg/mL, 500pg/mL, 250pg/mL, 125pg/mL, 62.5pg/mL, 31.2pg/mL human IL-6R alpha standard solutions into the precoated 96-well plate. Add 0.1 mL of the sample diluent buffer into the control well (Zero well). Add 0.1 mL of each properly diluted sample of human cell culture supernates, serum, plasma(heparin, EDTA, citrate) or urine to each empty well. It is recommended that each human IL-6R alpha standard solution and each sample be measured in duplicate.

Blood Product Anticoagulant: Heparin Sodium

ELISA Dilution: 31.2pg/mL-2000pg/mL

Probenmenge: 100 μL

Plattentyp: Pre-coated

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: RT,4 °C,-20 °C

Informationen zur Lagerung: Store vials at 4°C prior to opening. Centrifuge product if not completely clear after standing at room temperature. This product is stable for 6 months at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage freeze at -20°C or below for 12 months. Avoid cycles of freezing and thawing.

Details zu IL6RA

Target: IL6RA (Interleukin 6 Receptor, alpha (IL6RA))

Andere Bezeichnung: IL-6R alpha (IL6RA Produkte)

Synonyme: IL6R1 ELISA Kit, Il6ra ELISA Kit, CD126 ELISA Kit, IL-6R-1 ELISA Kit, IL-6RA ELISA Kit, IL6Q ELISA Kit, IL6RA ELISA Kit, IL6RQ ELISA Kit, gp80 ELISA Kit, IL-6R ELISA Kit, Il6r ELISA Kit, interleukin 6 receptor ELISA Kit, interleukin 6 receptor, alpha ELISA Kit, Il6r ELISA Kit, IL6R ELISA Kit, Il6ra ELISA Kit

Gen-ID: 3570

NCBI Accession: NP_000556

UniProt: A0N0L5

Pathways: JAK-STAT Signalweg, Autophagie, Growth Factor Binding, Cancer Immune Checkpoints