RANKL ELISA Kit
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- Target Alle RANKL (TNFSF11) ELISA Kits anzeigen
- RANKL (TNFSF11) (Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11))
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Reaktivität
- Maus
- Nachweismethode
- Colorimetric
- Methodentyp
- Sandwich ELISA
- Detektionsbereich
- 62.5 pg/mL - 4000 pg/mL
- Untere Nachweisgrenze
- 62.5 pg/mL
- Applikation
- ELISA
- Verwendungszweck
- Sandwich ELISA for Quantitative Detection of Antigen
- Proben
- Cell Culture Supernatant, Plasma (EDTA - heparin), Serum
- Analytische Methode
- Quantitative
- Produktmerkmale
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Synonyms: CD254, CD254 antigen, hRANKL2, ODF, OPGL, OPTB2, Osteoclast differentiation factor, Osteoprotegerin ligand, RANKL, receptor activator of nuclear factor kappa B ligand, Receptor activator of nuclear factor kappa-B ligand, sOdf, soluble form, TNF-related activation-induced cytokine, TNF11_HUMAN, Tnfsf11, TRANCE, tumor necrosis factor (ligand) superfamily, member 11, Tumor necrosis factor ligand superfamily member 11
Background: Receptor activator of nuclear factor kappa-B ligand(RANKL), also known as tumor necrosis factor ligand superfamily member 11(TNFSF11), is a protein that in humans is encoded by the TNFSF11 gene. This gene encodes a member of the tumor necrosis factor(TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. This gene is mapped to chromosome13q14.11. Targeted disruption of the related gene in mice led to severe osteopetrosis and a lack of osteoclasts. The deficient mice exhibited defects in early differentiation of T and B lymphocytes, and failed to form lobulo-alveolar mammary structures during pregnancy. This gene may play an important role in enhanced bone-resorption in humoral hypercalcemia of malignancy.
Gene Name: TNFSF11
Production: Natural and recombinant mouse TNFSF11. There is no detectable cross-reactivity with other relevant proteins.
Standard: Expression system for standard: NSO, Immunogen sequence: R72-D316
- Top Product
- Discover our top product TNFSF11 ELISA Kit
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- Applikationshinweise
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Application Note: Useful in Sandwich ELISA for Quantitative Detection of Antigen. Aliquot 0.1 mL per well of the 4000pg/mL, 2000pg/mL,1000pg/mL, 500pg/mL, 250pg/mL, 125pg/mL, 62.5pg/mL mouse TNFSF11 standard solutions into the precoated 96-well plate. Add 0.1 mL of the sample diluent buffer into the control well (Zero well). Add 0.1 mL of each properly diluted sample of mouse cell culture supernates, serum or plasma(heparin, EDTA) to each empty well. It is recommended that each mouse TNFSF11 standard solution and each sample be measured in duplicate.
Blood Product Anticoagulant: Heparin Sodium
ELISA Dilution: 62.5pg/mL-4000pg/mL
- Probenmenge
- 100 μL
- Plattentyp
- Pre-coated
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Lagerung
- RT,4 °C,-20 °C
- Informationen zur Lagerung
- Store vials at 4°C prior to opening. Centrifuge product if not completely clear after standing at room temperature. This product is stable for 6 months at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage freeze at -20°C or below for 12 months. Avoid cycles of freezing and thawing.
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- Target Alle RANKL (TNFSF11) ELISA Kits anzeigen
- RANKL (TNFSF11) (Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11))
- Andere Bezeichnung
- TNFSF11 - RANKL (TNFSF11 Produkte)
- Synonyme
- CD254 ELISA Kit, ODF ELISA Kit, OPGL ELISA Kit, OPTB2 ELISA Kit, RANKL ELISA Kit, TRANCE ELISA Kit, hRANKL2 ELISA Kit, sOdf ELISA Kit, TNFSF11 ELISA Kit, Ly109l ELISA Kit, OPG ELISA Kit, Trance ELISA Kit, cd254 ELISA Kit, odf ELISA Kit, opgl ELISA Kit, optb2 ELISA Kit, rankl ELISA Kit, sodf ELISA Kit, tnfsf11 ELISA Kit, trance ELISA Kit, TNF superfamily member 11 ELISA Kit, tumor necrosis factor (ligand) superfamily, member 11 ELISA Kit, TNF receptor superfamily member 11b ELISA Kit, TNF superfamily member 11 L homeolog ELISA Kit, TNFSF11 ELISA Kit, Tnfsf11 ELISA Kit, TNFRSF11B ELISA Kit, tnfsf11.L ELISA Kit
- Gen-ID
- 21943
- NCBI Accession
- NP_035743
- UniProt
- O35235
- Pathways
- NF-kappaB Signalweg
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