CD93 ELISA Kit

Produktnummer ABIN6720325

Produktdetails CD93 ELISA Kit

Target: CD93

Reaktivität: Human

Nachweismethode: Colorimetric

Methodentyp: Sandwich ELISA

Detektionsbereich: 78 pg/mL - 5000 pg/mL

Untere Nachweisgrenze: 78 pg/mL

Applikation: ELISA

Verwendungszweck: Sandwich ELISA for Quantitative Detection of Antigen

Proben: Cell Culture Supernatant, Plasma (EDTA - heparin), Saliva, Serum, Urine

Analytische Methode: Quantitative

Produktmerkmale:

Synonyms: C1q receptor 1, C1q/MBL/SPA receptor, C1qR, C1qR(p), C1qr1, C1QR1_HUMAN, C1qRp, CD93, CD93 antigen, CD93 Molecule, CDw93, Complement component 1 q subcomponent receptor 1, Complement component C1q receptor, dJ737E23.1, ECSM3, Matrix remodeling associated protein 4, Matrix remodelling associated 4, Matrix-remodeling-associated protein 4, MXRA4

Background: CD93 (Cluster of Differentiation 93) is a protein that in humans is encoded by the CD93 gene. CD93 belongs to the Group XIV C-Type lectin family and is mapped to 20p11.21. The protein encoded by this gene is a cell-surface glycoprotein and type I membrane protein that was originally identified as a myeloid cell-specific marker. The encoded protein was once thought to be a receptor for C1q, but now is thought to instead be involved in intercellular adhesion and in the clearance of apoptotic cells. The intracellular cytoplasmic tail of this protein has been found to interact with moesin, a protein known to play a role in linking transmembrane proteins to the cytoskeleton and in the remodelling of the cytoskeleton. It has also showed that this receptor is a positive marker for all bone marrow-repopulating stem cells because it is expressed on both CD34-negative and CD34-positive stem cells from umbilical cord blood and adult bone marrow. In addition, highly purified lineage-negative cells with the CD93 protein not only have bone marrow-repopulating capacity but also can differentiate into human hepatocytes in vivo.

Gene Name: CD93

Production: Natural and recombinant human CD93. There is no detectable cross-reactivity with other relevant proteins.

Standard: Expression system for standard: NSO, Immunogen sequence: A24-K580

Anwendungsinformationen

Applikationshinweise:

Application Note: Useful in Sandwich ELISA for Quantitative Detection of Antigen. Aliquot 0.1 mL per well of 5000pg/mL, 2500pg/mL, 1250pg/mL, 625pg/mL, 313pg/mL, 156pg/mL, 78pg/mL human CD93 standard solutions into the pre-coated 96-well plate. Add 0.1 mL of the sample diluent buffer into the control well (Zero well). Add 0.1 mL of each properly diluted sample of human cell culture supernates, serum, plasma( heparin, EDTA), saliva or urine to each empty well. We recommend that each human CD93 standard solution and each sample is measured in duplicate.

Blood Product Anticoagulant: Heparin Sodium

ELISA Dilution: 78pg/mL-5000pg/mL

Probenmenge: 100 μL

Plattentyp: Pre-coated

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: RT,4 °C,-20 °C

Informationen zur Lagerung: Store vials at 4°C prior to opening. Centrifuge product if not completely clear after standing at room temperature. This product is stable for 6 months at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage freeze at -20°C or below for 12 months. Avoid cycles of freezing and thawing.

Details zu CD93

Target: CD93

Andere Bezeichnung: CD93 - C1qR (CD93 Produkte)

Synonyme: 6030404G09Rik ELISA Kit, AA145088 ELISA Kit, AA4.1 ELISA Kit, AW555904 ELISA Kit, C1qr1 ELISA Kit, C1qrp ELISA Kit, Ly68 ELISA Kit, C1QR1 ELISA Kit, C1qR(P) ELISA Kit, C1qRP ELISA Kit, CDw93 ELISA Kit, ECSM3 ELISA Kit, MXRA4 ELISA Kit, dJ737E23.1 ELISA Kit, C1qRp ELISA Kit, CD93 antigen ELISA Kit, CD93 molecule ELISA Kit, Cd93 ELISA Kit, CD93 ELISA Kit

Gen-ID: 22918

NCBI Accession: NP_036204

UniProt: Q9NPY3