KLRC1 Produkte
(Killer Cell Lectin-Like Receptor Subfamily C, Member 1 (KLRC1))
Kategorien
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed. [provided by RefSeq, Jul 2008].
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Ausgewählte KLRC1 Kategorien
KLRC1 Antikörper
High quality antibodies with extensive validation data.
KLRC1 ELISA Kits
Reliable ELISA kits for a wide range of species.
KLRC1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene KLRC1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IF, FACS, IHC (p)
Validierungen
- (6)
Kat. Nr.
ABIN652569
Menge
200 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, IHC
Validierungen
- (3)
Kat. Nr.
ABIN7161640
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB
Validierungen
- (3)
Kat. Nr.
ABIN517356
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene KLRC1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6730533
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6730532
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene KLRC1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (5)
Kat. Nr.
ABIN7275339
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (4)
Kat. Nr.
ABIN7275338
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN7275335
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren KLRC1 Produkten
: "Membrane bound IL-21 based NK cell feeder cells drive robust expansion and metabolic activation of NK cells." in: Scientific reports, Vol. 9, Issue 1, pp. 14916, (2019) (PubMed).: "The ANXA1 released from intestinal epithelial cells alleviate DSS-induced colitis by improving NKG2A expression of Natural Killer cells." in: Biochemical and biophysical research communications, Vol. 478, Issue 1, pp. 213-20, (2016) (PubMed).
: "Interferon Alpha Induces Sustained Changes in NK Cell Responsiveness to Hepatitis B Viral Load Suppression In Vivo." in: PLoS pathogens, Vol. 12, Issue 8, pp. e1005788, (2016) (PubMed).
: "IL-21-Induced MHC Class II+ NK Cells Promote the Expansion of Human Uncommitted CD4+ Central Memory T Cells in a Macrophage Migration Inhibitory Factor-Dependent Manner." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 197, Issue 1, pp. 85-96, (2016) (PubMed).
: "CD3(bright)CD56(+) T cells associate with pegylated interferon-alpha treatment nonresponse in chronic hepatitis B patients." in: Scientific reports, Vol. 6, pp. 25567, (2016) (PubMed).
: "Human Induced Pluripotent Stem Cells Are Targets for Allogeneic and Autologous Natural Killer (NK) Cells and Killing Is Partly Mediated by the Activating NK Receptor DNAM-1." in: PLoS ONE, Vol. 10, Issue 5, pp. e0125544, (2015) (PubMed).
: "Overexpression of CD85j in TNBC patients inhibits Cetuximab-mediated NK-cell ADCC but can be restored with CD85j functional blockade." in: European journal of immunology, Vol. 45, Issue 5, pp. 1560-9, (2015) (PubMed).
: "WNT5A transforms intestinal CD8αα⁺ IELs into an unconventional phenotype with pro-inflammatory features." in: BMC gastroenterology, Vol. 15, pp. 173, (2015) (PubMed).
: "Regulatory Dendritic Cells Restrain NK Cell IFN-γ Production through Mechanisms Involving NKp46, IL-10, and MHC Class I-Specific Inhibitory Receptors." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 5, pp. 2141-8, (2015) (PubMed).
: "Up-regulation of activating and inhibitory NKG2 receptors in allogeneic and autologous hematopoietic stem cell grafts." in: Journal of experimental & clinical cancer research : CR, Vol. 34, pp. 98, (2015) (PubMed).
Synonyme und alternative Namen zu KLRC1
killer cell lectin like receptor C1 (Klrc1), killer cell lectin like receptor C1 (KLRC1), NKG2-A/NKG2-B type II integral membrane protein-like (NKG2A), killer cell lectin-like receptor subfamily C, member 3 (KLRC3), killer cell lectin-like receptor subfamily C, member 1 (KLRC1), killer cell lectin-like receptor subfamily C, member 1 (Klrc1), CD159A, CD159a, KLRC1, NKG2, NKG2-A, NKG2A, NKG2B, rNKG2ABezeichner auf Proteinebene für KLRC1
- natural killer cell protein group 2-A (NKG2A)
- CD159 antigen-like family member A
- NK cell receptor A
- NKG2-A/B-activating NK receptor
- NKG2-A/NKG2-B type II integral membrane protein
- killer cell lectin-like receptor subfamily C, member 1
- C-lectin type II protein
- NKG2-1/B activating NK receptor
- NKG2-A/B type II integral membrane protein
- natural killer cell lectin
- natural killer group protein 2
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