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KPNA4 Produkte

(Karyopherin (Importin) alpha 4 (KPNA4))

Kategorien

The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs). Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. The protein encoded by this gene shares the sequence similarity with Xenopus importin-alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen. [provided by RefSeq, Jul 2008].

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Ausgewählte KPNA4 Kategorien

KPNA4 Antikörper

High quality antibodies with extensive validation data.

KPNA4 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene KPNA4 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, IF
Validierungen
  • (1)
  • (24)
Kat. Nr. ABIN3015855
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, ELISA
Validierungen
  • (1)
  • (6)
Kat. Nr. ABIN185160
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC, IF
Validierungen
  • (4)
Kat. Nr. ABIN7156122
Menge 100 μg
Datenblatt Datenblatt

Empfohlene KPNA4 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6229027
Menge 96 tests
Datenblatt Datenblatt

Empfohlene KPNA4 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1308922
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7423609
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (1)
Kat. Nr. ABIN2724406
Menge 20 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren KPNA4 Produkten

Solomon, Stepto, Au, Adachi, Diaper, Hall, Rekhi, Boudi, Tziortzouda, Lee, Smith, Bridi, Spinelli, Dearlove, Humphrey, Gallo, Troakes, Fanto, Soller, Rogelj, Parsons, Shaw, Hortobágyi, Hirth: "A feedback loop between dipeptide-repeat protein, TDP-43 and karyopherin-α mediates C9orf72-related neurodegeneration." in: Brain : a journal of neurology, Vol. 141, Issue 10, pp. 2908-2924, (2019) (PubMed).

Watanabe, Sugawara, Noguchi, Hirose, Ōmura, Sunazuka, Horie: "Jietacins, azoxy natural products, as novel NF-κB inhibitors: Discovery, synthesis, biological activity, and mode of action." in: European journal of medicinal chemistry, Vol. 178, pp. 636-647, (2019) (PubMed).

Li, Lu, Huang, Lv: "Porcine circovirus type 2 inhibits inter-β expression by targeting Karyopherin alpha-3 in PK-15 cells." in: Virology, Vol. 520, pp. 75-82, (2018) (PubMed).

Yang, Lu, Wei, Guo, Liu, Luo, Fisch, Li: "Inhibition of KPNA4 attenuates prostate cancer metastasis." in: Oncogene, Vol. 36, Issue 20, pp. 2868-2878, (2017) (PubMed).

Jeong, Kim, Lee, Cha, Khadka, Cho, Chung: "Akt-mediated phosphorylation increases the binding affinity of hTERT for importin α to promote nuclear translocation." in: Journal of cell science, Vol. 128, Issue 12, pp. 2287-301, (2015) (PubMed).

Zhang, Dong, Zhang, He, Chen, Cao, Li, Xiao, Lu, Pan: "Identification of a novel nuclear localization signal of baculovirus late expression factor 11." in: Virus research, Vol. 184, pp. 111-9, (2014) (PubMed).

Ishiguro, Ando, Maeda, Watanabe, Goto: "Cutting edge: tubulin ? functions as an adaptor in NFAT-importin ? interaction." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 186, Issue 5, pp. 2710-3, (2011) (PubMed).

Huenniger, Krämer, Soom, Chang, Köhler, Depping, Kehlenbach, Kaether: "Notch1 signaling is mediated by importins alpha 3, 4, and 7." in: Cellular and molecular life sciences : CMLS, Vol. 67, Issue 18, pp. 3187-96, (2010) (PubMed).

Ao, Danappa Jayappa, Wang, Zheng, Kung, Rassart, Depping, Kohler, Cohen, Yao: "Importin alpha3 interacts with HIV-1 integrase and contributes to HIV-1 nuclear import and replication." in: Journal of virology, Vol. 84, Issue 17, pp. 8650-63, (2010) (PubMed).

Theiss, Jenkins, Okoro, Klapproth, Merlin, Sitaraman: "Prohibitin inhibits tumor necrosis factor alpha-induced nuclear factor-kappa B nuclear translocation via the novel mechanism of decreasing importin alpha3 expression." in: Molecular biology of the cell, Vol. 20, Issue 20, pp. 4412-23, (2009) (PubMed).

Synonyme und alternative Namen zu KPNA4

karyopherin subunit alpha 4 (KPNA4), ARM repeat superfamily protein (MOS6), importin alpha 3 (LOC100533341), karyopherin (importin) alpha 4 (Kpna4), karyopherin subunit alpha 4 (Kpna4), karyopherin alpha 4 (importin alpha 3) S homeolog (kpna4.S), karyopherin alpha 4 (importin alpha 3) (kpna4), 6, 1110058D08Rik, ATIMPALPHA3, IMPA-3, impa3, importin, IMPORTIN ALPHA 3, IMPORTIN ALPHA ISOFORM 3, IPOA3, ipoa3, LOC100224013, MODIFIER OF SNC1, QIP1, qip1, SRP3, srp3, T10M13.16, T10M13_16, wu:fa56d07, wu:fa66g10, wu:fe14c04, wu:fi04h11, wu:fi19b05

Bezeichner auf Proteinebene für KPNA4

  • importin alpha Q1
  • importin subunit alpha-3
  • importin subunit alpha-4
  • karyopherin subunit alpha-4
  • importin alpha 3
  • karyopherin alpha 4 (importin alpha 3)
  • qip1
  • karyopherin (importin) alpha 4
  • predicted role in nuclear import
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