KPNB1 Produkte
(Karyopherin (Importin) beta 1 (KPNB1))
Kategorien
Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2013].
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Ausgewählte KPNB1 Kategorien
KPNB1 Antikörper
High quality antibodies with extensive validation data.
KPNB1 ELISA Kits
Reliable ELISA kits for a wide range of species.
KPNB1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene KPNB1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IF
Validierungen
- (5)
Kat. Nr.
ABIN6142997
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Rat
Applikation
WB, ELISA, IHC, FACS, IF
Validierungen
- (5)
Kat. Nr.
ABIN185516
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, FACS, IHC (p)
Validierungen
- (3)
Kat. Nr.
ABIN390792
Menge
400 μL
Datenblatt
Datenblatt
Empfohlene KPNB1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6957266
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN5656173
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene KPNB1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1308928
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN667986
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7415023
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren KPNB1 Produkten
: "Antiviral activity of a purine synthesis enzyme reveals a key role of deamidation in regulating protein nuclear import." in: Science advances, Vol. 5, Issue 10, pp. eaaw7373, (2019) (PubMed).: "Osteoblast regulation via ligand-activated nuclear trafficking of the oxytocin receptor." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 46, pp. 16502-7, (2014) (PubMed).
: "Multiple importins function as nuclear transport receptors for the Rev protein of human immunodeficiency virus type 1." in: The Journal of biological chemistry, Vol. 281, Issue 30, pp. 20883-90, (2006) (PubMed).
: "Spatial coordination of spindle assembly by chromosome-mediated signaling gradients." in: Science (New York, N.Y.), Vol. 309, Issue 5739, pp. 1373-6, (2005) (PubMed).
: "Perturbation of SUMOlation enzyme Ubc9 by distinct domain within nucleoporin RanBP2/Nup358." in: The Journal of biological chemistry, Vol. 277, Issue 7, pp. 4755-63, (2002) (PubMed).
: "Exercise training attenuates coronary smooth muscle phenotypic modulation and nuclear Ca2+ signaling." in: American journal of physiology. Heart and circulatory physiology, Vol. 283, Issue 6, pp. H2397-410, (2002) (PubMed).
: "Role of importin-beta in coupling Ran to downstream targets in microtubule assembly." in: Science (New York, N.Y.), Vol. 291, Issue 5504, pp. 653-6, (2001) (PubMed).
: "The path of RNA through nuclear pores: apparent entry from the sides into specialized pores." in: Journal of cell science, Vol. 113 Pt 2, pp. 291-302, (2000) (PubMed).
: "Protein import into nuclei: association and dissociation reactions involving transport substrate, transport factors, and nucleoporins." in: Cell, Vol. 83, Issue 5, pp. 683-92, (1996) (PubMed).
: "Identification of a protein complex that is required for nuclear protein import and mediates docking of import substrate to distinct nucleoporins." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 92, Issue 5, pp. 1769-73, (1995) (PubMed).
Synonyme und alternative Namen zu KPNB1
importin beta-1 subunit (AFUA_1G15720), importin beta-1 subunit (AOR_1_1974174), Importin beta-1 subunit (Bm1_57540), importin beta-1 subunit (PMAA_065830), importin beta-1 subunit (AFLA_083750), importin beta-1 subunit (TSTA_085870), importin beta-1 subunit (BDBG_07509), importin beta-1 subunit (MCYG_00039), karyopherin (importin) beta 1 L homeolog (kpnb1.L), importin beta 1 (LOC100533387), karyopherin subunit beta 1 (KPNB1), karyopherin (importin) beta 1 (Kpnb1), karyopherin subunit beta 1 (Kpnb1), AA409963, Afu1g15720, AO090005001133, imb1, IMB1, impnb, Impnb, ipo1, IPO1, ipob, IPOB, ntf97, NTF97Bezeichner auf Proteinebene für KPNB1
- Importin beta-1 subunit
- importin beta-1 subunit
- importin beta 1
- PTAC97
- importin 1
- importin 90
- importin subunit beta-1
- importin-90
- karyopherin subunit beta-1
- nuclear factor p97
- pore targeting complex 97 kDa subunit
- SCG
- importin beta
- Importin beta
- karyopherin,beta 1
- nuclear factor P97
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