LAMTOR1 Produkte
(Late Endosomal/lysosomal Adaptor, MAPK and mTOR Activator 1 (LAMTOR1))
Kategorien
Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, recruits the Rag GTPases and the mTORC1 complex to lysosomes, a key step in activation of the TOR signaling cascade by amino acids. Directly responsible for anchoring the Ragulator complex to membranes. Also required for late endosomes/lysosomes biogenesis it may regulate both the recycling of receptors through endosomes and the MAPK signaling pathway through recruitment of some of its components to late endosomes. May be involved in cholesterol homeostasis regulating LDL uptake and cholesterol release from late endosomes/lysosomes. May also play a role in RHOA activation (By similarity).
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Ausgewählte LAMTOR1 Kategorien
LAMTOR1 Antikörper
High quality antibodies with extensive validation data.
LAMTOR1 ELISA Kits
Reliable ELISA kits for a wide range of species.
LAMTOR1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene LAMTOR1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IF, IHC
Validierungen
- (3)
Kat. Nr.
ABIN6143083
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
IF, ELISA, IHC
Validierungen
- (2)
Kat. Nr.
ABIN7167068
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene LAMTOR1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6968205
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene LAMTOR1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Xenopus tropicalis
Source
Yeast
Validierungen
Kat. Nr.
ABIN1675037
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren LAMTOR1 Produkten
: "LAMTOR2/LAMTOR1 complex is required for TAX1BP1-mediated xenophagy." in: Cellular microbiology, Vol. 21, Issue 4, pp. e12981, (2019) (PubMed).: "mTOR activates the VPS34-UVRAG complex to regulate autolysosomal tubulation and cell survival." in: The EMBO journal, Vol. 34, Issue 17, pp. 2272-90, (2015) (PubMed).
: "The late endosomal adaptor p14 is a macrophage host-defense factor against Salmonella infection." in: Journal of cell science, Vol. 125, Issue Pt 11, pp. 2698-708, (2012) (PubMed).
: "MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB." in: Autophagy, Vol. 8, Issue 6, pp. 903-14, (2012) (PubMed).
: "Proteomic analysis of endosomes from genetically modified p14/MP1 mouse embryonic fibroblasts." in: Proteomics, Vol. 10, Issue 22, pp. 4117-27, (2010) (PubMed).
Synonyme und alternative Namen zu LAMTOR1
late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 (LAMTOR1), late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 (Lamtor1), late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 S homeolog (lamtor1.S), 2400001E08Rik, C11orf59, c11orf59, C15H11orf59, flj20625, p18, p27RF-Rho, p27rf-rho, PDRO, Pdro, pdro, Ragulator1, ragulator1Bezeichner auf Proteinebene für LAMTOR1
- RhoA activator C11orf59
- late endosomal/lysosomal adaptor and MAPK and MTOR activator 1
- lipid raft adaptor protein p18
- p27Kip1-releasing factor from RhoA
- p27kip1 releasing factor from RhoA
- protein associated with DRMs and endosomes
- ragulator complex protein LAMTOR1
- ragulator complex protein PDRO
- RhoA activator C11orf59 homolog
- p27RF-Rho
- rhoA activator C11orf59 homolog
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