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LASS5 Produkte

(LAG1 Homolog, Ceramide Synthase 5 (LASS5))

Kategorien

May be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing mainly one fatty acid donor (N-linked palmitoyl- (C16) ceramide) in a fumonisin B1-independent manner (By similarity).

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Ausgewählte LASS5 Kategorien

LASS5 Antikörper

High quality antibodies with extensive validation data.

LASS5 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene LASS5 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation ELISA, WB, IHC, IF
Validierungen
  • (3)
Kat. Nr. ABIN7147471
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Mouse
Applikation ELISA, WB, IF (cc), IF (p), IHC (p), IHC (fro)
Validierungen
  • (1)
Kat. Nr. ABIN709406
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB
Validierungen
  • (1)
Kat. Nr. ABIN7268175
Menge 100 μL
Datenblatt Datenblatt

Empfohlene LASS5 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1309179
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3103268
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Mouse
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3129163
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren LASS5 Produkten

Zabielski, Blachnio-Zabielska, Lanza, Gopala, Manjunatha, Jakaitis, Persson, Gransee, Klaus, Schimke, Jensen, Nair: "Impact of insulin deprivation and treatment on sphingolipid distribution in different muscle subcellular compartments of streptozotocin-diabetic C57Bl/6 mice." in: American journal of physiology. Endocrinology and metabolism, Vol. 306, Issue 5, pp. E529-42, (2014) (PubMed).

Separovic, Breen, Joseph, Bielawski, Pierce, VAN Buren, Gudz: "Ceramide synthase 6 knockdown suppresses apoptosis after photodynamic therapy in human head and neck squamous carcinoma cells." in: Anticancer research, Vol. 32, Issue 3, pp. 753-60, (2012) (PubMed).

Separovic, Breen, Joseph, Bielawski, Pierce, VAN Buren, Gudz: "siRNA-mediated down-regulation of ceramide synthase 1 leads to apoptotic resistance in human head and neck squamous carcinoma cells after photodynamic therapy." in: Anticancer research, Vol. 32, Issue 7, pp. 2479-85, (2012) (PubMed).

Kim, Qiao, Toop, Morris, Don: "A fluorescent assay for ceramide synthase activity." in: Journal of lipid research, Vol. 53, Issue 8, pp. 1701-7, (2012) (PubMed).

Yamane, Miyazawa, Moriya, Abe, Yamane et al.: "D,L-Threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol (DL-PDMP) increases endoplasmic reticulum stress, autophagy and apoptosis accompanying ceramide accumulation via ceramide synthase 5 protein ..." in: Biochimie, Vol. 93, Issue 9, pp. 1446-59, (2011) (PubMed).

Min, Mesika, Sivaguru, Van Veldhoven, Alexander, Futerman, Alexander: "(Dihydro)ceramide synthase 1 regulated sensitivity to cisplatin is associated with the activation of p38 mitogen-activated protein kinase and is abrogated by sphingosine kinase 1." in: Molecular cancer research : MCR, Vol. 5, Issue 8, pp. 801-12, (2007) (PubMed).

Spassieva, Seo, Jiang, Bielawski, Alvarez-Vasquez, Jazwinski, Hannun, Obeid: "Necessary role for the Lag1p motif in (dihydro)ceramide synthase activity." in: The Journal of biological chemistry, Vol. 281, Issue 45, pp. 33931-8, (2006) (PubMed).

Lahiri, Futerman: "LASS5 is a bona fide dihydroceramide synthase that selectively utilizes palmitoyl-CoA as acyl donor." in: The Journal of biological chemistry, Vol. 280, Issue 40, pp. 33735-8, (2005) (PubMed).

Riebeling, Allegood, Wang, Merrill, Futerman: "Two mammalian longevity assurance gene (LAG1) family members, trh1 and trh4, regulate dihydroceramide synthesis using different fatty acyl-CoA donors." in: The Journal of biological chemistry, Vol. 278, Issue 44, pp. 43452-9, (2003) (PubMed).

Synonyme und alternative Namen zu LASS5

ceramide synthase 5 (CERS5), ceramide synthase 5 (cers5), ceramide synthase 5 S homeolog (cers5.S), ceramide synthase 5 (Cers5), 2310081H14Rik, AU045339, AW544927, lass5, LASS5, Lass5, trh4, Trh4

Bezeichner auf Proteinebene für LASS5

  • LAG1 homolog, ceramide synthase 5
  • LAG1 longevity assurance homolog 5-like
  • LAG1 longevity assurance homolog 5
  • TRAM homolog 4
  • longevity assurance homolog 5
  • translocating chain-associating membrane protein homolog 4
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