LAT Produkte
(Linker For Activation of T Cells (LAT))
Kategorien
The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
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Ausgewählte LAT Kategorien
LAT Antikörper
High quality antibodies with extensive validation data.
LAT ELISA Kits
Reliable ELISA kits for a wide range of species.
LAT Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene LAT Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IP, FACS
Validierungen
- (2)
- (5)
Kat. Nr.
ABIN302069
Menge
0.1 mg
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, IHC, IF
Validierungen
- (7)
Kat. Nr.
ABIN7074502
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC, IP, IF
Validierungen
- (5)
Kat. Nr.
ABIN7127705
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene LAT ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6968299
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6968298
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6957484
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene LAT Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7123771
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1309185
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN2130291
Menge
50 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren LAT Produkten
: "Endothelial-derived plasma exosome proteins in Alzheimer's disease angiopathy." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 34, Issue 4, pp. 5967-5974, (2021) (PubMed).: "Rab6-dependent retrograde traffic of LAT controls immune synapse formation and T cell activation." in: The Journal of experimental medicine, Vol. 215, Issue 4, pp. 1245-1265, (2019) (PubMed).
: "PRR7 is a transmembrane adaptor protein expressed in activated T cells involved in regulation of T cell receptor signaling and apoptosis." in: The Journal of biological chemistry, Vol. 286, Issue 22, pp. 19617-29, (2011) (PubMed).
: "LAT and NTAL mediate immunoglobulin E-induced sustained extracellular signal-regulated kinase activation critical for mast cell survival." in: Molecular and cellular biology, Vol. 27, Issue 12, pp. 4406-15, (2007) (PubMed).
: "Topography of signaling molecules as detected by electron microscopy on plasma membrane sheets isolated from non-adherent mast cells." in: Journal of immunological methods, Vol. 328, Issue 1-2, pp. 139-51, (2007) (PubMed).
: "Topography of plasma membrane microdomains and its consequences for mast cell signaling." in: European journal of immunology, Vol. 36, Issue 10, pp. 2795-806, (2006) (PubMed).
: "Transmembrane adaptor molecules: a new category of lymphoid-cell markers." in: Blood, Vol. 107, Issue 1, pp. 213-21, (2005) (PubMed).
: "Structural basis for differential recognition of tyrosine-phosphorylated sites in the linker for activation of T cells (LAT) by the adaptor Gads." in: The EMBO journal, Vol. 23, Issue 7, pp. 1441-51, (2004) (PubMed).
: "Negative regulation of mast cell signaling and function by the adaptor LAB/NTAL." in: The Journal of experimental medicine, Vol. 200, Issue 8, pp. 1001-13, (2004) (PubMed).
: "Right time, right place: the organization of membrane proximal signaling." in: Seminars in immunology, Vol. 17, Issue 1, pp. 35-49, (2004) (PubMed).
Synonyme und alternative Namen zu LAT
linker for activation of T-cells (LAT), linker for activation of T cells (lat), linker for activation of T cells (Lat), LAT, lat, LAT1, pp36Bezeichner auf Proteinebene für LAT
- linker for activation of T cells
- 36 kDa phospho-tyrosine adapter protein
- 36 kDa phospho-tyrosine adaptor protein
- linker for activation of T cells, transmembrane adaptor
- linker for activation of T-cells family member 1
- p36-38
- pp36
- linker protein
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